Six developmental trajectories ID'd in children with autism

April 2, 2012
Six developmental trajectories ID'd in children with autism
Six longitudinal developmental trajectories have been identified among children with autism, with significant heterogeneity seen in developmental pathways within these trajectories, according to a study published online April 2 in Pediatrics.

(HealthDay) -- Six longitudinal developmental trajectories have been identified among children with autism, with significant heterogeneity seen in developmental pathways within these trajectories, according to a study published online April 2 in Pediatrics.

Christine Fountain, Ph.D., of Columbia University in New York City, and colleagues described the typical longitudinal developmental trajectories of 6,975 children with autism (aged 2 to 14 years) who were enrolled with the California Department of Developmental Services. Nine items for social, communication, and repetitive behavior functioning were evaluated to construct a score sequence. Using group-based latent trajectory modeling, typical trajectories were identified and the odds of classification within each trajectory were assessed.

The researchers identified six typical patterns of social, communication, and functioning. Significant was seen in developmental pathways within these trajectories, and children whose symptoms were least severe at first diagnosis had a tendency to improve more quickly than those who were more severely affected. One group, representing about 10 percent of children, experienced rapid gains, transitioning from severely affected to high functioning. There was a correlation between and trajectory outcomes; high levels of functioning were more likely among children with non-Hispanic, white, well-educated mothers, and rapid gains were unlikely among with or less-educated mothers.

"It is important to observe the developmental pathways children with autism follow over time to understand the pace and timing of changes," the authors write. "More work is needed to discover whether these longitudinal patterns will help us not only to understand the diversity of autism but also to better target interventions and improve treatment."

Explore further: New study shows minority toddlers with autism are more delayed than affected Caucasian peers

More information: Abstract
Full Text

Related Stories

New study shows minority toddlers with autism are more delayed than affected Caucasian peers

February 21, 2012
The first prospective study of ethnic differences in the symptoms of autism in toddlers shows that children from a minority background have more delayed language, communication and gross motor skills than Caucasian children ...

ADHD symptoms worsen quality of life for individuals with autism

September 19, 2011
Research supported by the Autism Speaks Autism Treatment Network (ATN), demonstrating that symptoms of attention deficit and hyperactivity worsen quality of life for individuals with autism spectrum disorders (ASD), was presented ...

Mothers of kids with autism earn less, study shows

March 19, 2012
(HealthDay) -- Mothers of children with autism and autism spectrum disorders earn significantly less than what mothers of children who have no health limitations earn, a new study has found.

Cleveland Clinic Children's Hospital launches study to genetically test for autism

February 29, 2012
Cleveland Clinic Children's Hospital has launched a study to determine whether genetic markers can be used to help identify children who are at risk of developing autism.

Recommended for you

Late-breaking mutations may play an important role in autism

July 17, 2017
A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism. A team led by investigators at Boston Children's Hospital ...

Females with autism show greater difficulty with day-to-day tasks than male counterparts

July 14, 2017
Women and girls with autism may face greater challenges with real world planning, organization and other daily living skills, according to a study published in the journal Autism Research.

Researchers investigate possible link between carnitine deficiency and autism

July 13, 2017
Researchers are always looking for new clues to the causes of autism, with special emphasis on prevention or treatment. At Baylor College of Medicine, Dr. Arthur Beaudet has been following clinical and genetic clues in patients ...

How children look at mom's face is influenced by genetic factors and altered in autism

July 12, 2017
New research has uncovered compelling evidence that genetics plays a major role in how children look at the world and whether they have a preference for gazing at people's eyes and faces or at objects.

Oxytocin improves social abilities in some kids with autism, study finds

July 10, 2017
Children with autism showed improved social behavior when treated with oxytocin, a hormone linked to social abilities, according to a new study by researchers at the Stanford University School of Medicine. Children with low ...

Possible early diagnosis of autism spectrum disorder

June 29, 2017
Measuring a set of proteins in the blood may enable earlier diagnosis of autism spectrum disorder (ASD), according to a study from the Peter O'Donnell Jr. Brain Institute at UT Southwestern Medical Center.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.