Mobility key to quality of life for MS sufferers

May 18, 2012

(Medical Xpress) -- Reduced mobility among patients with secondary‐progressive multiple sclerosis (SPMS) is associated with a decline in quality of life, according to new data presented today at the 7th World Congress of NeuroRehabilitation in Melbourne.

According to  UNSW's Associate Professor of Neuroscience, Arun Krishnan, whether or not symptomatic treatments that improve might also make a positive contribution to ’ quality of life is an important focus for future research.

Professor Krishnan’s research looked at data derived from 160 placebo treated MS patients whose speed was measured using the Timed 25 Foot Walk (T25FW) test and then correlated this with quality of life measures (including a physical component summary scale, physical function, bodily pain and general health) over a two year period.

Overall, slower walking speed was associated with a decline in quality of life over two years. This association between walking speed and quality of life was independent of any treatment because the subjects were derived from the placebo arm of a clinical trial.

At two years, data showed that patients walked on average 19% slower. Physical component scores (like physical function and general health) declined in patients who walked more than 0.15 metres/second slower at month 24 compared with baseline and improved in the small number who walked greater than 0.15 metres/second faster.

Professor Krishnan says the findings are important as they suggest a clinical focus on the treatment of reduced mobility in MS patients might deliver significant benefits in the future to patients with secondary‐progressive .

“There are limited treatment options for patients whose MS is progressing and who are at the ‘secondary progressive’ phase. Whether treatments that improve walking also positively influence health‐related quality of life in MS patients is certainly an intriguing question for the future,” said Professor Krishnan.

Explore further: Interventional radiologists see 'significant' symptom relief in MS patients

Related Stories

Interventional radiologists see 'significant' symptom relief in MS patients

March 25, 2012
Researchers who investigated the connection between chronic cerebrospinal venous insufficiency (a reported condition characterized as a blockage in the veins that drain blood from the brain and spinal cord and returns it ...

Muscling in on multiple sclerosis

January 26, 2012
Multiple sclerosis (MS), a neurodegenerative disease, causes periodic attacks of neurologic symptoms such as limb weakness and mobility defects. And while MS patients' walking abilities and muscle strength are examined on ...

Recommended for you

Mind-body therapies immediately reduce unmanageable pain in hospital patients

July 25, 2017
Mindfulness training and hypnotic suggestion significantly reduced acute pain experienced by hospital patients, according to a new study published in the Journal of General Internal Medicine.

Researchers report new system to study chronic hepatitis B

July 25, 2017
Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections. ...

Research examines lung cell turnover as risk factor and target for treatment of influenza pneumonia

July 24, 2017
Influenza is a recurring global health threat that, according to the World Health Organization, is responsible for as many as 500,000 deaths every year, most due to influenza pneumonia, or viral pneumonia. Infection with ...

Scientists propose novel therapy to lessen risk of obesity-linked disease

July 24, 2017
With obesity related illnesses a global pandemic, researchers propose in the Journal of Clinical Investigation using a blood thinner to target molecular drivers of chronic metabolic inflammation in people eating high-fat ...

Raccoon roundworm—a hidden human parasite?

July 24, 2017
The raccoon that topples your trashcan and pillages your garden may leave more than just a mess. More likely than not, it also contaminates your yard with parasites—most notably, raccoon roundworms (Baylisascaris procyonis).

Google searches can be used to track dengue in underdeveloped countries

July 20, 2017
An analytical tool that combines Google search data with government-provided clinical data can quickly and accurately track dengue fever in less-developed countries, according to new research published in PLOS Computational ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.