Pleasure eating triggers body's reward system and may stimulate overeating

May 3, 2012, The Endocrine Society

When eating is motivated by pleasure, rather than hunger, endogenous rewarding chemical signals are activated which can lead to overeating, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The phenomenon ultimately affects body mass and may be a factor in the continuing rise of obesity.

"'Hedonic hunger' refers to the desire to for pleasure, and to enjoy the taste, rather than to restore the body's energy needs,"says Palmiero Monteleone, MD, of the University of Naples SUN in Italy and lead author of this study. "For example, desiring and eating a piece of cake even after a satiating meal is consumption driven by pleasure and not by energy deprivation. The physiological process underlying hedonic eating is not fully understood, but it is likely that endogenous substances regulating reward mechanisms like the hormone ghrelin and chemical compounds such as 2-arachidonoylglycerol (2-AG) are involved."

In this study, researchers assessed eight satiated healthy adults, aged 21󈞍 years, feeding them each their personal favorite food and, later, a less-palatable food of equal caloric and nutrient value. Researchers periodically measured 2-AG and ghrelin levels. The plasma levels of ghrelin and 2-AG increased during hedonic eating, with the favorite foods, but not with non-hedonic eating. This increase suggests an activation of the chemical reward system, which overrides the body's signal that enough has been eaten to restore energy.

"Hedonic may powerfully stimulate in an environment where highly palatable foods are omnipresent, and contribute to the surge in obesity,"says Monteleone. "Understanding the physiological mechanisms underlying this eating behaviour may shed some light on the obesity epidemic. Further research should confirm and extend our results to patients with obesity or with other eating disorders in order to better understand the phenomenon of hedonic eating."

The article, "Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans. A pilot study," appears in the June 2012 issue of JCEM.

Explore further: Ghrelin increases willingness to pay for food

Related Stories

Ghrelin increases willingness to pay for food

July 12, 2011
Research to be presented at the upcoming annual meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, suggests that ghrelin, ...

Ghrelin likely involved in why we choose 'comfort foods' when stressed

June 23, 2011
We are one step closer to deciphering why some stressed people indulge in chocolate, mashed potatoes, ice cream and other high-calorie, high-fat comfort foods.

Feeding hormone ghrelin modulates ability of rewarding food to evoke dopamine release

July 12, 2011
New research findings to be presented at the upcoming annual meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that ...

Recommended for you

Researchers illustrate how muscle growth inhibitor is activated, could aid in treating ALS

January 19, 2018
Researchers at the University of Cincinnati (UC) College of Medicine are part of an international team that has identified how the inactive or latent form of GDF8, a signaling protein also known as myostatin responsible for ...

Bioengineered soft microfibers improve T-cell production

January 18, 2018
T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, ...

Weight flux alters molecular profile, study finds

January 17, 2018
The human body undergoes dramatic changes during even short periods of weight gain and loss, according to a study led by researchers at the Stanford University School of Medicine.

Secrets of longevity protein revealed in new study

January 17, 2018
Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent Yale-led study, researchers revealed the three-dimensional structure ...

The HLF gene protects blood stem cells by maintaining them in a resting state

January 17, 2018
The HLF gene is necessary for maintaining blood stem cells in a resting state, which is crucial for ensuring normal blood production. This has been shown by a new research study from Lund University in Sweden published in ...

Magnetically applied MicroRNAs could one day help relieve constipation

January 17, 2018
Constipation is an underestimated and debilitating medical issue related to the opioid epidemic. As a growing concern, researchers look to new tools to help patients with this side effect of opioid use and aging.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.