Early vaccinations not linked to celiac disease in sweden

June 25, 2012
Early vaccinations not linked to celiac disease in sweden
Early vaccinations do not seem to influence the risk of celiac disease among infants, nor do changes in the vaccination program explain the celiac disease epidemic, according to a Swedish study published online June 25 in Pediatrics.

(HealthDay) -- Early vaccinations do not seem to influence the risk of celiac disease (CD) among infants, nor do changes in the vaccination program explain the CD epidemic, according to a Swedish study published online June 25 in Pediatrics.

To investigate whether changes in the national Swedish coincided with changes in the incidence of CD in infants, Anna Myléus, Ph.D., M.D., from Umeå University in Sweden, and colleagues analyzed data from the National Swedish Childhood Register and performed a population-based incident case-referent study of infants. Questionnaires and child health clinic records were used to obtain exposure information. The responses to the following vaccines were examined: diphtheria/tetanus, pertussis (acellular), polio (inactivated), Haemophilus influenza type b (conjugated), measles/ mumps/rubella, and live attenuated bacillus Calmette-Guérin (BCG; given to children with increased tuberculosis risk).

The researchers found that the introduction of the pertussis vaccine coincided in time with decreasing CD incidence rates, but there was no association seen between CD and vaccination against pertussis (odds ratio, 0.91; 95 percent confidence interval, 0.60 to 1.4), Haemophilus influenza type b, or measles/mumps/rubella. BCG correlated with decreased risk for CD (adjusted odds ratio, 0.54), but discontinuation of general BCG vaccination had no impact on the cumulative incidence of CD at age 15 years.

"The Swedish epidemic of CD is not fully understood, and changes in the vaccination program or coverage do not contribute to the explanation," the authors write. "We found no epidemiologic evidence that the immunologic response to increases CD risk."

Abstract

Full Text (subscription or payment may be required)

Explore further: Study: No significant rise in seizure risk from common kids' vaccine

Related Stories

Study: No significant rise in seizure risk from common kids' vaccine

February 22, 2012
(HealthDay) -- Children who receive a combination vaccine known as DTaP-IPV-Hib have no significant increased risk of febrile seizure, a convulsion triggered by a fever, during the week after vaccination, researchers in Denmark ...

Study examines prevalence of conduct disorder among families of Mexican migrants in the US

December 5, 2011
The prevalence of conduct disorder (CD) appears to have increased substantially across generations of the Mexican-origin population after migration to the United States, however this increase was observed more for nonaggressive ...

Recommended for you

Lactic acid bacteria can protect against Influenza A virus, study finds

December 13, 2017
Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts ...

Lyme bacteria survive 28-day course of antibiotics months after infection

December 13, 2017
Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and American Journal of Pathology, that seem to support ...

Aging impairs innate immune response to flu

December 13, 2017
Aging impairs the immune system's response to the flu virus in multiple ways, weakening resistance in older adults, according to a Yale study. The research reveals why older people are at increased risk of illness and death ...

Drug blocks Zika, other mosquito-borne viruses in cell cultures

December 12, 2017
If there was a Mafia crime family of the virus world, it might be flaviviruses.

Study seeks to aid diagnosis, management of catatonia

December 11, 2017
Catatonia, a syndrome of motor, emotional and behavioral abnormalities frequently characterized by muscular rigidity and a trance-like mental stupor and at times manifesting with great excitement or agitation, can occur during ...

New compound stops progressive kidney disease in its tracks

December 7, 2017
Progressive kidney diseases, whether caused by obesity, hypertension, diabetes, or rare genetic mutations, often have the same outcome: The cells responsible for filtering the blood are destroyed. Reporting today in Science, ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.