Link between vascular disease and disc height loss examined

June 8, 2012
Link between vascular disease and disc height loss examined
The association between vascular disease, as measured by abdominal aortic calcifications, and disc height loss is independent of cardiovascular disease and is largely explained by patient age, gender, and body mass index, according to a study published in the April issue of The Spine Journal.

(HealthDay) -- The association between vascular disease, as measured by abdominal aortic calcifications (AACs), and disc height loss is independent of cardiovascular disease and is largely explained by patient age, gender, and body mass index (BMI), according to a study published in the April issue of The Spine Journal.

Pradeep Suri, M.D., of the Veterans Affairs Boston Healthcare System, and colleagues conducted a cross-sectional, community-based study utilizing a sample of 435 participants from the . Quantitative AAC scores, measured using computed tomography scans, were grouped as tertiles of no (reference), low, and high calcification, and the association with disc height loss was assessed.

In crude analyses, the researchers found that, compared with no calcification, low AAC and high AAC were significantly associated with disc height loss (odds ratio [OR], 2.05 and 2.24, respectively). The relationship between AAC and disc height loss was not attenuated by hypertension, smoking, diabetes, or hypercholesterolemia. However, after adjustment for patient age, sex, and BMI, there was an attenuation in the associations between low AAC (OR, 1.20; P = 0.51) and high AAC (OR, 0.74; P = 0.42) and disc height loss.

"AAC was associated with disc height loss in this community-based population," the authors write. "This relationship was independent of . However, the association of AAC with disc height loss was explained by the effects of age, sex, and BMI."

Several authors disclosed to the pharmaceutical and medical device industries.

Explore further: Pattern of disc degeneration impacts low back pain

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Pattern of disc degeneration impacts low back pain

April 12, 2012
(HealthDay) -- Contiguous, multilevel disc degeneration (CMDD) is associated with increased likelihood of low back pain (LBP) and pain severity compared with skipped level disc degeneration (SLDD), according to a study published ...

Lumbar disc degeneration more likely in overweight and obese adults

January 30, 2012
One of the largest studies to investigate lumbar spine disc degeneration found that adults who are overweight or obese were significantly more likely to have disc degeneration than those with a normal body mass index (BMI). ...

Study examines use of waist measures among overweight and obese adolescents

April 2, 2012
Waist measures (waist circumference, waist to height ratio) in conjunction with body mass index appear to be associated with lipid and blood pressure assessments among overweight and obese adolescents, according to a report ...

Recommended for you

Groundbreaking investigative effort identifies gonorrhea vaccine candidates

September 19, 2017
Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

Snail fever progression linked to nitric oxide production

September 14, 2017
Bilharzia, caused by a parasitic worm found in freshwater called Schistosoma, infects around 200 million people globally and its advance can lead to death, especially in children in developing countries.

Systems analysis points to links between Toxoplasma infection and common brain diseases

September 13, 2017
More than 2 billion people - nearly one out of every three humans on earth, including about 60 million people in the United States - have a lifelong infection with the brain-dwelling parasite Toxoplasma gondii.

Study clears important hurdle toward developing an HIV vaccine

September 13, 2017
An international team of researchers has demonstrated a way of overcoming one of the major stumbling blocks that has prevented the development of a vaccine against HIV: the ability to generate immune cells that stay in circulation ...

As 'flesh-eating' Leishmania come closer, a vaccine against them does, too

September 13, 2017
Parasites that ulcerate the skin, can disfigure the face, and may fatally mutilate its victim's internal organs are creeping closer to the southern edges of the United States.

Promising clinical trial results could give doctors a new tool against drug-resistant strains of malaria parasite

September 13, 2017
Tulane University researchers have developed a new drug that is effective against non-severe cases of malaria, according to results from an FDA-supervised clinical trial published in the latest issue of The Lancet Infectious ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.