Disinfection caps cut CLABSI cases in half

January 3, 2013

Central line-associated bloodstream infections (CLABSI) dropped by 52 percent when an alcohol-impregnated disinfection cap was used instead of standard scrubbing protocol, according to a new study published in the January issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

A team of researchers from NorthShore University HealthSystem conducted a study of in order to determine the efficacy of 70 percent alcohol-impregnated disinfection caps over the standard cleaning protocol, which involves scrubbing the catheter hub with an alcohol disinfectant wipe prior to accessing the lines. In a three-phased study, contamination rates among 799 patients sampled from three hospitals declined from a baseline of 12.7 percent using the standard cleaning protocol, to 5.5 percent when the disinfection cap was used, and increased back to 12 percent when the intervention was removed and was reinstated. Infection rates at four hospitals declined from a baseline of 1.43 per 1,000 line days to 0.69 during the intervention, and returned to 1.31 per 1,000 line days when the intervention was suspended.

The researchers estimated that system-wide implementation of the disinfecting caps would prevent 21 CLABSIs and four deaths each year.

A central line-associated bloodstream infection is a serious infection that occurs when germs enter the bloodstream through a catheter (tube) that doctors often place in a large vein in the neck, chest, or groin to give medication or fluids or to collect blood for medical tests. Contaminated catheter hubs can be a cause of such infections.

"Catheter hub requires a thorough scrub, and compliance varies," state the authors. "The approach of using a continuously applied alcohol-impregnated sponge as a cap on the hub for a standard approach to catheter care may eliminate the problem of teaching healthcare providers one additional disinfection process they need to use as part of their busy patient care schedule."

Explore further: Few hospitals aggressively combat catheter-associated urinary tract infections

More information: "Continuous passive disinfection of catheter hubs prevents contamination and bloodstream infection," by Marc-Oliver Wright, Jackie Tropp, Donna M. Schora, Mary Dillon-Grant, Kari Peterson, Sue Boehm, Ari Robicsek, and Lance R. Peterson appears in the American Journal of Infection Control, Volume 41, Issue 1 (January 2013).

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