Post-pregnancy deterioration in glycemic control in T1DM

Post-pregnancy deterioration in glycemic control in T1DM
Women with type 1 diabetes experience post-pregnancy deterioration in glycemic control and sustained weight gain, according to research published online Dec. 18 in Diabetes Care.

(HealthDay)—Women with type 1 diabetes experience post-pregnancy deterioration in glycemic control and sustained weight gain, according to research published online Dec. 18 in Diabetes Care.

Katarzyna Cyganek, M.D., Ph.D., of the University Hospital in Krakow, Poland, and colleagues examined post-pregnancy glycemic control and weight changes in 254 women (mean age, 28.3 years) with (duration, 12.0 ± 7.7 years) who had singleton pregnancies. The women were followed post-delivery for a median of 20 months.

The researchers found that the mean A1C decreased from 6.9 percent preconception to 5.7 percent during the third trimester. The mean weight gain during pregnancy was 14.4 kg. Within six months of delivery, A1C increased significantly, by 0.8 percent versus the last trimester, and it further deteriorated by 0.8 percent up to the end of follow-up. Compared with preconception baseline, body weight was 4.4 kg higher and was 2.5 kg/m² higher within six months after delivery, and were 2.5 kg and 0.9 kg/m² higher, respectively, at the end of follow-up. Women with planned pregnancies (117 women) experienced worse A1C at more than 12 months after delivery compared with before conception, while for women with unplanned pregnancies the level was similar to that of pre-gestation.

"In conclusion, type 1 diabetic women showed post-pregnancy deterioration in glycemic control. They were also unable to return to their pre-pregnancy weight," the authors write. "Type 1 diabetic women seem to require special medical attention after delivery to maintain their within therapeutic targets."


Explore further

Pre-op factors predict post-gastric op glycemic response

More information: Abstract
Full Text (subscription or payment may be required)
Journal information: Diabetes Care

Health News Copyright © 2013 HealthDay. All rights reserved.

Citation: Post-pregnancy deterioration in glycemic control in T1DM (2013, February 14) retrieved 29 November 2021 from https://medicalxpress.com/news/2013-02-post-pregnancy-deterioration-glycemic-t1dm.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors