Low vitamin D linked with lower kidney function after transplantation

Vitamin D deficiency may decrease kidney function in transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The finding suggests that vitamin D supplementation may help improve the health of kidney transplant recipients.

is prevalent in patients with . It's not clear how this affects patients after they receive a kidney transplant. To investigate, Frank Bienaimé, MD (Université Paris Descartes and INSERM and Assistance Publique Hopitaux de Paris) and his colleagues studied a group of 634 kidney recipients who underwent transplantation between January 2005 and June 2010.

The researchers found that low vitamin D levels measured at three months after transplantation were linked with lower kidney function and increased kidney scarring at 12 months post-transplant. Other hormones involved with mineral metabolism were not predictors of kidney function or scarring after one year.

"This result suggests that maintaining vitamin D concentration within the normal range would prevent renal function deterioration after renal transplantation," said Dr. Bienaimé. "Vitamin D supplementation, a simple and inexpensive treatment, may improve transplantation outcomes." He encouraged the design of to evaluate the potential of vitamin D supplements to maintain kidney function following transplantation.


Explore further

Drug fails to help kidney transplant recipients

More information: The article, entitled "Vitamin D Status and Outcomes After Renal Transplantation," will appear online on March 28, 2013, doi: 10.1681/ASN.2012060614
Citation: Low vitamin D linked with lower kidney function after transplantation (2013, March 28) retrieved 16 July 2019 from https://medicalxpress.com/news/2013-03-vitamin-d-linked-kidney-function.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more