Pot smoking linked to some metabolic changes

April 19, 2013
Pot smoking linked to some metabolic changes
Regularly smoking pot is associated with visceral adiposity and adipose tissue insulin resistance, but not other metabolic changes such as impaired β-cell function or hepatic steatosis, according to a study published online March 25 in Diabetes Care.

(HealthDay)—Regularly smoking pot is associated with visceral adiposity and adipose tissue insulin resistance, but not other metabolic changes such as impaired β-cell function or hepatic steatosis, according to a study published online March 25 in Diabetes Care.

Ranganath Muniyappa, M.D., Ph.D., from the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Md., and colleagues compared abdominal fat depots, intrahepatic fat content, insulin sensitivity, and beta-cell function in 30 cannabis smokers (median of six joints a day for a median of 9.5 years) and 30 matched controls.

The researchers found that, although carbohydrate intake and percent calories from carbohydrates were significantly higher for the cannabis group, total energy intake was similar in both groups. Cannabis smokers had a significantly higher percent abdominal visceral fat (18 versus 12 percent), significantly lower plasma high-density lipoprotein cholesterol (49 versus 55 mg/dL), and a significantly lower adipocyte insulin resistance index and percent suppression during an .

"Chronic cannabis smoking was associated with visceral adiposity and adipose tissue but not with hepatic steatosis, insulin insensitivity, impaired pancreatic β-cell function, or glucose intolerance," Muniyappa and colleagues conclude.

Explore further: Obese adults with excess abdominal fat, insulin resistance may have higher risk of type 2 diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Obese adults with excess abdominal fat, insulin resistance may have higher risk of type 2 diabetes

September 18, 2012
Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body's internal organs) and biomarkers of insulin resistance had an associated increased risk for the development of type 2 diabetes ...

Study shows overeating impairs brain insulin function, can lead to diabetes and obesity

October 17, 2012
New research from Mount Sinai School of Medicine sheds light on how overeating can cause a malfunction in brain insulin signaling, and lead to obesity and diabetes. Christoph Buettner, MD, PhD, Associate Professor of Medicine ...

Insulin sensitivity normally highest after breakfast

October 26, 2012
(HealthDay)—In healthy people without diabetes, glucose responsiveness tends to be higher after breakfast, which may have implications for the design of closed-loop insulin delivery systems for diabetes patients, according ...

Estrogen may improve pathway-selective insulin resistance

February 14, 2013
(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin action on glucose ...

Recommended for you

Getting fat to 'talk' again could lower blood glucose and weight

August 22, 2017
Diabetes is a tough disease to manage. Oral medications, insulin shots, close monitoring of blood sugar, dietary changes and exercise can all factor into a person's treatment regimen. Now researchers are exploring a novel, ...

Biochemical 'fingerprints' reveal diabetes progression

August 21, 2017
Researchers from Umeå University in Sweden describe a new method to study biochemical changes that occur in the pancreas during the development of diabetes. The method, recently published in Scientific Reports, is based ...

In a nutshell: Walnuts activate brain region involved in appetite control

August 17, 2017
Packed with nutrients linked to better health, walnuts are also thought to discourage overeating by promoting feelings of fullness. Now, in a new brain imaging study, researchers at Beth Israel Deaconess Medical Center (BIDMC) ...

Smart mat detects early warning signs of foot ulcers

August 16, 2017
While completing his residency in anesthesiology at Massachusetts General Hospital in the mid-2000s, Jon Bloom saw his fair share of foot amputations among patients with diabetes. The culprit: infected foot ulcers.

The best place to treat type 1 diabetes might be just under your skin

August 14, 2017
A group of U of T researchers have demonstrated that the space under our skin might be an optimal location to treat type 1 diabetes (T1D).

New measure of insulin-making cells could gauge diabetes progression, treatment

August 10, 2017
Researchers at the University of Wisconsin-Madison have developed a new measurement for the volume and activity of beta cells, the source of the sugar-regulating hormone insulin.

2 comments

Adjust slider to filter visible comments by rank

Display comments: newest first

Canis Maximus
5 / 5 (1) Apr 19, 2013
Will someone please explain:
"significantly lower plasma high-density lipoprotein cholesterol (49 versus 55 mg/dL), and a significantly lower adipocyte insulin resistance index and percent free fatty acids suppression during an oral glucose tolerance test."

for someone not as versed in diabetic etymology?
Mauricio
1 / 5 (1) Apr 19, 2013
http://healthland...-weight/

and this is my personal experience. I know a whole lot of cannabis smokers, and most are skinny, skinnier than the average by far.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.