Diabetic retinopathy severity inversely tied to cognition

July 1, 2013
Diabetic retinopathy severity inversely tied to cognition
For patients with type 2 diabetes, the severity of diabetic retinopathy is inversely linked to cognitive impairment, according to a study published online April 30 in Diabetes Care.

(HealthDay)—For patients with type 2 diabetes, the severity of diabetic retinopathy (DR) is inversely linked to cognitive impairment, according to a study published online April 30 in Diabetes Care.

Roxanne R. Crosby-Nwaobi, Ph.D., from King's College London, and colleagues recruited 380 patients with type 2 diabetes from a population-based program. Participants were grouped by severity of DR: no/mild DR (252 patients) or proliferative (PDR; 128 patients). Participants underwent psychosocial evaluation; ; ophthalmic and physical examination, including blood assays; and cognitive assessments.

The researchers found that there was a significant inverse correlation between the severity of DR and cognitive impairment. The observed variance was partially explained by ethnicity (16 percent), education (7.3 percent), and retinopathy status (6.8 percent). Cognitive impairment scores on the Addenbrooke's Cognitive Examination-Revised were significantly lower in the no/mild DR group versus the PDR group. Twelve percent of the no/mild DR group and 5 percent of the PDR group had positive screening results for dementia or significant cognitive impairment, based on the Mini-Mental State Examination cut-off scores.

"Patients with minimal DR demonstrated more cognitive impairment than those with advanced DR," the authors write. "The increased prevalence of cognitive impairment in diabetes may be associated with factors other than evident retinal ."

Explore further: Cardiac disease linked to higher risk of mental impairment

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Cardiac disease linked to higher risk of mental impairment

January 28, 2013
Cardiac disease is associated with increased risk of mild cognitive impairment such as problems with language, thinking and judgment—particularly among women with heart disease, a Mayo Clinic study shows. Known as nonamnestic ...

Alzheimer's and low blood sugar in diabetes may trigger a vicious cycle

June 10, 2013
Diabetes-associated episodes of low blood sugar may increase the risk of developing dementia, while having dementia or even milder forms of cognitive impairment may increase the risk of experiencing low blood sugar, according ...

Retinopathy severity linked to cardiovascular outcome

January 25, 2013
(HealthDay)—For individuals with type 2 diabetes, incident cardiovascular outcomes are determined not only by the severity of diabetic retinopathy but also by its progression, according to research published online Dec. ...

Mild cognitive impairment at Parkinson's disease diagnosis linked with higher risk for early dementia

March 25, 2013
Mild cognitive impairment at the time of Parkinson disease (PD) diagnosis appears to be associated with an increased risk for early dementia in a Norwegian study, according to a report published Online First by JAMA Neurology.

Late-life depression associated with prevalent mild cognitive impairment, increased risk of dementia

December 31, 2012
Depression in a group of Medicare recipients ages 65 years and older appears to be associated with prevalent mild cognitive impairment and an increased risk of dementia, according to a report published Online First by Archives ...

Recommended for you

Team provides insight into glucagon's role in diabetic heart disease

February 21, 2018
A UT Southwestern study reveals the hormone glucagon's importance to the development of insulin resistance and cardiac dysfunction during Type 2 diabetes, presenting opportunities to develop new therapies for diabetic diseases ...

Physical exercise reduces risk of developing diabetes: study

February 20, 2018
Exercising more reduces the risk of diabetes and could see seven million fewer diabetic patients across mainland China, Hong Kong and Taiwan, according to new research.

Some viruses produce insulin-like hormones that can stimulate human cells—and have potential to cause disease

February 19, 2018
Every cell in your body responds to the hormone insulin, and if that process starts to fail, you get diabetes. In an unexpected finding, scientists at Joslin Diabetes Center have identified four viruses that can produce insulin-like ...

Researchers discover link between gut and type 1 diabetes

February 19, 2018
Scientists have found that targeting micro-organisms in the gut, known as microbiota, could have the potential to help prevent type 1 diabetes.

Researchers find existing drug effective at preventing onset of type 1 diabetes

February 15, 2018
A drug commonly used to control high blood pressure may also help prevent the onset of type 1 diabetes in up to 60 percent of those at risk for the disease, according to researchers at the University of Colorado Anschutz ...

Chemist designs diabetic treatment minus harmful side effects

February 9, 2018
A chemist in the College of Arts and Sciences (A&S) has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.