Kids' allergies may correlate with omega-3, omega-6 lipid levels in cord blood

July 10, 2013

Children with high proportions of poly-unsaturated fatty acids (PUFA) in cord blood at birth are more likely to develop respiratory and skin allergies in their early teens, according to research published July 10 in the open access journal PLOS ONE by Malin Barman and colleagues from the Chalmers University of Technology, Sweden.

The researchers followed nearly 800 children born in 1996-97 for diagnosis of allergies at age 13, and studied a subset of 44 who were diagnosed with respiratory allergies, 37 with chronic skin rashes and 48 who did not suffer allergies. Cord blood samples taken at birth from these participants revealed that individuals who suffered allergies later in life had higher proportions of unsaturated fatty acids.

Children with allergies at age 13 had higher proportions of omega-3 and omega-6 PUFAs in cord blood samples taken at birth. Compared to healthy children, also had lower levels of mono-unsaturated fats in their cord blood. The risk of respiratory allergies in children with higher PUFA levels was equally significant in children with allergic and non-allergic mothers. The study says, "The mechanism by which these lipids affect allergy development is unknown, but may involve dampening of the in infancy needed for proper maturation of the infant's immune system."

Explore further: 1997 to 2011 saw increase in allergies among US children

More information: Barman M, Johansson S, Hesselmar B, Wold AE, Sandberg A-S, et al. (2013) High Levels of Both n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids in Cord Serum Phospholipids Predict Allergy Development. PLOS ONE 8(7): e67920. doi:10.1371/journal.pone.0067920

Related Stories

1997 to 2011 saw increase in allergies among US children

May 3, 2013
(HealthDay)—For U.S. children aged younger than 18 years, the prevalence of allergies increased from 1997 to 2011, with age, race/ethnicity, and income all affecting the prevalence, according to a May data brief issued ...

Food allergies tied to impaired growth in kids

February 25, 2013
(HealthDay)—Food allergies appear to affect children's growth, a new study suggests.

Race linked to childhood food allergies, not environmental allergies

February 23, 2013
Research conducted at Henry Ford Hospital shows that race and possibly genetics play a role in children's sensitivity to developing allergies.

Living in US raises risk of allergies, study shows

April 29, 2013
Children born outside the United States have a lower risk of asthma, skin and food allergies, and living in the United States for a decade may raise a person's allergy risk, said a study on Monday.

Study indicates link between high vitamin D levels in expectant mothers and increased infant allergy risks

February 27, 2013
Pregnant women should avoid taking vitamin D supplements. Substitution appears to raise the risk of children developing a food allergy after birth. This was the conclusion drawn from a new survey carried out by the Helmholtz ...

Dampness key cause of asthma in children

June 27, 2013
(Medical Xpress)—The largest-ever worldwide study of the link between damp homes and respiratory and allergic conditions has significant implications for New Zealand children's health.

Recommended for you

Study suggests same gut bacteria can trigger different immune responses depending on environment

July 24, 2017
(Medical Xpress)—A group of researchers affiliated with several institutions in the U.S. has found that one type of gut bacteria triggers different kinds of immune responses depending on the state of the environment they ...

Genetic immune deficiency could hold key to severe childhood infections

July 18, 2017
A gene mutation making young children extremely vulnerable to common viruses may represent a new type of immunodeficiency, according to a University of Queensland researcher.

What are the best ways to diagnose and manage asthma?

July 18, 2017
What are the best ways to diagnose and manage asthma in adults? This can be tricky because asthma can stem from several causes and treatment often depends on what is triggering the asthma.

Large multi-ethnic study identifies many new genetic markers for lupus

July 17, 2017
Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

Study finds molecular explanation for struggles of obese asthmatics

July 17, 2017
A large, bouquet-shaped molecule called surfactant protein A, or SP-A, may explain why obese asthma patients have harder-to-treat symptoms than their lean and overweight counterparts, according to a new study led by scientists ...

Team identifies potential cause for lupus

July 14, 2017
Leading rheumatologist and Feinstein Institute for Medical Research Professor Betty Diamond, MD, may have identified a protein as a cause for the adverse reaction of the immune system in patients suffering from lupus. A better ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.