A new generation of dialysis devices

March 3, 2014 by Juliette Fhij

Kidney dialysis is a heavy treatment to undergo and has many side effects. Scientist Prof Dimitrios Stamatialis is starting a new research project into the development of new dialysis membranes for longer and better blood detoxification. The project belongs to The Life Science and Health (LSH) Impuls program and is performed in collaboration between industry, the Dutch Kidney Foundation, Maastricht University and the Maastricht University Medical Center (UMC+). Prof Stamatialis is affiliated with the MIRA research institute of the University of Twente.

Hemodialysis is by far the most common form of dialysis undergone by who are dependent on it. This involves purifying the blood outside of the patient's body using an artificial kidney. The artificial kidney is housed in a large dialysis machine. Treatment usually takes place two or three times a week and each session lasts around three to five hours. While dialysis is a lifesaving treatment, it has a significant effect on the kidney patient's body and life. Since the treatment is not continuous, waste products accumulate between dialysis sessions and the patient's fluid balance fluctuates significantly. This means that kidney patients feel exhausted more quickly and are often nauseous. Headaches and itching are also common complaints.

Longer and better

Prof Dimitrios Stamatialis is starting research into the development of a new device based on new blood-compatible biomaterials combined with adsorbent particles for toxin removal. These filters can be used for longer periods of time and are expected to remove a broad range of toxins. The filters currently used generally remove only small uremic toxins.

"If patients are able to undergo more frequently and / or for longer periods of time, their  fluid balance  is better," explains Prof Stamatialis. "The waste products in the blood  do not accumulate between treatments and this means that patients feel better. I am also focusing on the development of better filters."

Lightweight portable device

Longer, better and smaller are the keywords of Stamatialis' research. Prof Stamatialis: "My long term ambition is the development of a lightweight portable device which patients can use for a longer period of time. In this new project, we will make significant progress in this direction. We will develop the new devices and test them on small animals."

Explore further: Overnight dialysis boosts kidney health—while reducing risk of heart disease

Related Stories

Overnight dialysis boosts kidney health—while reducing risk of heart disease

October 18, 2013
Receiving dialysis at home while sleeping not only improves kidney health and quality of life for people with kidney disease, it could also decrease their risk of heart disease, says new study presented at the Canadian Cardiovascular ...

Intensive dialysis in pregnant women with kidney failure benefits mother and baby

February 13, 2014
Intensive dialysis treatments in pregnant women with kidney failure lead to a higher proportion of live births than standard dialysis care, according to a study appearing in an upcoming issue of the Journal of the American ...

Investigational drug effective in treating iron deficiency in kidney disease patients on dialysis

November 9, 2013
Doctors at the North Shore-LIJ Health System on Saturday will present late-breaking data showing that an investigational drug Triferic is well tolerated and effective in treating iron deficiency in patients with chronic kidney ...

Intensive kidney dialysis indicates better survival rates than conventional dialysis

April 25, 2012
Patients suffering with end-stage renal disease could increase their survival chances by undergoing intensive dialysis at home rather than the conventional dialysis in clinics. A new study by Lawson Health Research Institute ...

New evidence of the benefits of home dialysis for kidney patients

June 21, 2011
Researchers at St. Michael's Hospital have found more evidence of the benefits of home dialysis for patients with kidney failure.

Home dialysis gains momentum

December 19, 2013
Of the 400,000 people on dialysis in the United States only 6 percent to 7 percent are treated with home dialysis. Yet, patients are significantly more likely to choose home dialysis if they are given that option. Home dialysis ...

Recommended for you

Researchers developing new tool to distinguish between viral, bacterial infections

July 28, 2017
Antibiotics are lifesaving drugs, but overuse is leading to one of the world's most pressing health threats: antibiotic resistance. Researchers at the University of Rochester Medical Center are developing a tool to help physicians ...

Finish your antibiotics course? Maybe not, experts say

July 27, 2017
British disease experts on Thursday suggested doing away with the "incorrect" advice to always finish a course of antibiotics, saying the approach was fuelling the spread of drug resistance.

Co-infection with two common gut pathogens worsens malnutrition in mice

July 27, 2017
Two gut pathogens commonly found in malnourished children combine to worsen malnutrition and impair growth in laboratory mice, according to new research published in PLOS Pathogens.

Phase 3 trial confirms superiority of tocilizumab to steroids for giant cell arteritis

July 26, 2017
A phase 3 clinical trial has confirmed that regular treatment with tocilizumab, an inhibitor of interleukin-6, successfully reduced both symptoms of and the need for high-dose steroid treatment for giant cell arteritis, the ...

A large-scale 'germ trap' solution for hospitals

July 26, 2017
When an infectious airborne illness strikes, some hospitals use negative pressure rooms to isolate and treat patients. These rooms use ventilation controls to keep germ-filled air contained rather than letting it circulate ...

Researchers report new system to study chronic hepatitis B

July 25, 2017
Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections. ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.