Diseases, Conditions, Syndromes

Higher eGFR at dialysis initiation tied to lower survival in children

(HealthDay)—In children with end-stage renal disease (ESRD), a higher estimated glomerular filtration rate (eGFR) at dialysis initiation is associated with lower survival, particularly among children whose initial treatment ...

Diseases, Conditions, Syndromes

Many older patients initiating dialysis experience functional decline

A new study published in CJASN found that functional decline within the first 6 months after initiating dialysis was highly prevalent in older adults at 17 centers in Netherlands, and the risk was higher in those with advanced ...

Medical research

Scientists engineer vascularized kidney tissue

Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have shown the feasibility of bioengineering vascularized functional renal tissues for kidney regeneration, developing a partial augmentation strategy that ...

Diseases, Conditions, Syndromes

Two treatments help dialysis patients with depression, study finds

For almost 50 years, hemodialysis has extended lives of people with chronic kidney disease. But when a patient first learns that their kidneys have failed and dialysis is necessary to survive, it can be a jolting overture ...

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Dialysis

In medicine, dialysis (from Greek "dialusis", meaning dissolution, "dia", meaning through, and "lusis", meaning loosening) is primarily used to provide an artificial replacement for lost kidney function (renal replacement therapy) due to renal failure. Dialysis may be used for very sick patients who have suddenly but temporarily, lost their kidney function (acute renal failure) or for quite stable patients who have permanently lost their kidney function (stage 5 chronic kidney disease). When healthy, the kidneys maintain the body's internal equilibrium of water and minerals (sodium, potassium, chloride, calcium, phosphorus, magnesium, sulfate) and the kidneys remove from the blood the daily metabolic load of fixed hydrogen ions. The kidneys also function as a part of the endocrine system producing erythropoietin and 1,25-dihydroxycholecalciferol (calcitriol). Dialysis is an imperfect treatment to replace kidney function because it does not correct the endocrine functions of the kidney. Dialysis treatments replace some of these functions through diffusion (waste removal) and ultrafiltration (fluid removal).

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