Trial continues after patient death: French heartmaker

March 4, 2014

French biomedical firm Carmat said Tuesday it would implant its experimental artificial heart into another three people, as planned, after the first recipient died.

In an email to AFP, the company said it was too soon to draw conclusions about the device's efficacy.

A 76-year-old recipient died over the weekend, 75 days after receiving the gadget, whose trials are being closely followed by French investors.

"It is premature to draw conclusions based on the outcomes from a single patient," said the the firm, whose stock was suspended at its own request on Tuesday.

"Carmat does not intend announcing the results of this trial until the implants and 30-day followup of all four intended four patients are complete."

The septuagenarian with terminal was one of four people, all with end-stage , selected for the experiment.

The trial would be considered a success if each of the four survive for at least a month.

Artificial hearts have been in use for many years as a temporary fix for patients with chronic heart problems.

Unlike these mostly synthetic pumps, the Carmat product aims to provide a longer-term solution—up to five years—to bridge the wait for a and enabling hospitalised patients to go back home and even resume work.

The device, a self-contained unit implanted in a patient's chest, is a mix of synthetic materials and animal tissue, and seeks to mimic the form and function of an actual human .

Nearly 100,000 people in Europe and the United States are in need of a , according to Carmat.

Explore further: Man with first artificial heart dies after 75 days

Related Stories

Man with first artificial heart dies after 75 days

March 3, 2014
A septuagenarian man who was fitted with the French biomedical firm Carmat's first artificial heart two and half months ago has died, a hospital statement said Monday.

French firm starts human trials of artificial heart

December 20, 2013
French biomedical firm Carmat said on Friday it had begun the first human trial of its prototype artificial heart, which aims at overcoming shortages of organs available for transplant.

Patient 'progressing' after first artificial heart implant in France

December 22, 2013
A 75-year-old man who this week became the first person to receive an artificial heart developed by French biomedical firm Carmat was progressing well, doctors said Saturday.

Artificial heart with Norwegian sensor

December 19, 2013
France is going to test an artificial heart on patients. The heart will contain a Norwegian pressure sensor.

Space technology informs artificial heart development

December 6, 2013
An artificial heart containing miniaturised space technology will soon beat inside a person, having now been approved for human trials in France.

FDA OKs HeartWare device for transplant patients

November 20, 2012
The Food and Drug Administration on Tuesday approved a new heart pump for patients with severe heart failure who are awaiting a heart transplant.

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.