Amblyopia Tx at young age results in good vision later

July 16, 2014
Amblyopia tx at young age results in good vision later

(HealthDay)—Most children treated for moderate amblyopia when younger than 7 years have good visual acuity at 15 years of age, according to a study published in the July issue of JAMA Ophthalmology.

Michael X. Repka, M.D., from Johns Hopkins University in Baltimore, and colleagues randomly assigned 419 children with amblyopia (visual acuity, 20/40 to 20/100) to either patching (minimum of six hours/day) or atropine sulfate eye drops (1 percent; one drop daily), for six months. After six months, was at the discretion of the investigator. An unselected subgroup of 188 children were enrolled into long-term follow-up two years after enrollment.

The researchers found that mean visual acuity in the amblyopic eye measured at 15 years was approximately 20/25 in 147 participants; 59.9 percent of amblyopic eyes had visual acuity of 20/25 or better and 33.3 percent had visual acuity of 20/20 or better. At 15 years of age, the mean interocular acuity difference (IOD) was 2.1 lines, with 48.3 percent having an IOD of two or more lines and 71.4 percent having an IOD of one or more lines. Nine participants (aged 10 to 15 years; 6.1 percent) had prescribed treatment other than spectacles. At the 15-year examination, better visual acuity was achieved in those who were younger than 5 years at the time of entry into the , compared with those aged 5 to 6 years (P < 0.001). There were no significant differences in of amblyopic and fellow eyes at 15 years of age when comparing original treatment with atropine or patching (P = 0.44 and 0.43, respectively).

"The results indicate that improvement occurring with amblyopia treatment is maintained until at least 15 years of ," the authors write.

Explore further: Supplementation of formula with LCPUFAs ups infant visual acuity

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Supplementation of formula with LCPUFAs ups infant visual acuity

December 17, 2012
(HealthDay)—For infants, supplementation of formula with long-chain polyunsaturated fatty acids (LCPUFAs) correlates with improved visual acuity in the first year of life, according to research published online Dec. 17 ...

New optical metrics can identify patients on 'fast track' to decreased vision

June 24, 2013
Sophisticated new optical quality metrics can identify older adults likely to have more rapid age-related declines in vision, suggests a study, "Factors Accounting for the 4-Year Change in Acuity in Patients Between 50 and ...

Study reports two-year outcomes of diabetic macular edema treatment

April 9, 2012
A randomized controlled trial involving patients with persistent clinically significant diabetic macular edema (swelling of the retina) suggests the greater efficacy of bevacizumab compared with macular laser therapy that ...

Innovative approaches to improve vision in children with tumors

February 28, 2014
Robert Avery, DO, MSCE, of Children's National Health System and colleagues are establishing innovative approaches with technology and medication to improve the vision of young children who have visual pathway glioma, a type ...

Recommended for you

Researchers report startling glaucoma protein discovery

October 20, 2017
A discovery in a protein associated with glaucoma was so unheard of that for over two years, researchers ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially ...

Curve-eye-ture: How to grow artificial corneas

October 19, 2017
Scientists at Newcastle University, UK, and the University of California have developed a new method to grow curved human corneas improving the quality and transparency - solely by controlling the behaviour of cells in a ...

Clinical study success for novel contact lens device aimed to improve glaucoma treatment

October 19, 2017
A novel contact lens device developed by University of Liverpool engineers to improve the treatment of glaucoma has been found to reliably track pressure changes in the eye and be wearable by people who took part in its first ...

Study indicates proof of concept for using a surrogate liquid biopsy to provide genetic profile of retinoblastoma tumors

October 12, 2017
Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age. If not diagnosed early, retinoblastoma may result in loss of one or both eyes and can be fatal. Unlike most cancers that are diagnosed ...

Farsighted children struggle with attention, study finds

October 10, 2017
Farsighted preschoolers and kindergartners have a harder time paying attention and that could put them at risk of slipping behind in school, a new study suggests.

New drug reduces rate of progression of incurable eye disease

October 4, 2017
An international study including researchers from the Centre for Eye Research Australia (CERA) has found a way to slow the progression of dry age-related macular degeneration (AMD) - one of the most common causes of vision ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.