Use of drug-eluting stents may cut in-hospital mortality
Apurva O. Badheka, M.D., of the Detroit Medical Center, and colleagues analyzed data from 665,804 PCI procedures to assess the association between stent type and in-hospital mortality.
The researchers found that the in-hospital mortality rate was higher in patients receiving BMS versus DES (1.4 versus 0.5 percent; P < 0.001). This association remained significant when adjusted for possible confounders (odds ratio [OR] for in-hospital mortality for DES versus BMS, 0.59; P < 0.001) or analyzed in propensity-matched cohorts (1.2 versus 0.7 percent; P < 0.001). Similar associations were observed in high-risk subgroups of patients, including those with diabetes (OR, 0.57), acute myocardial infarction and/or shock (OR, 0.53), age greater than 80 years (OR, 0.66), and multivessel PCI (OR, 0.55) (all P < 0.001).
"The patients receiving DES had both lower in-hospital mortality and combined end point of postprocedural mortality and complications compared with patients who got BMS," the authors write.
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