Polycaprolactone efficient for nasolabial fold treatment

January 15, 2015
Polycaprolactone efficient for nasolabial fold treatment

(HealthDay)—For patients with nasolabial folds (NLFs), treatment with a novel biostimulatory polycaprolactone (PCL)-based dermal filler is associated with improved long-lasting efficacy compared with nonanimal stabilized hyaluronic acid (NASHA)-based fillers. This finding was published online Jan. 6 in the Journal of Cosmetic Dermatology.

Hassan Galadari, M.D., from the United Arab Emirates University in Al Ain, and colleagues conducted a randomized split-face study to compare a novel PCL-based dermal filler with a NASHA-based dermal filler in 40 patients. The authors compared the safety, efficacy, and duration of cosmetic correction for the treatment of NLFs.

The researchers found that compared with NAHSA-based filler, NLFs treated with the PCL-based dermal filler showed statistically significant improvements on the Wrinkle Severity Rating Scale and greater improvements on the Global Aesthetic Improvement Scale at six, nine, and 12 months post-treatment. The products were found to be equivalent in terms of safety and tolerability.

"Our results suggest that PCL-based dermal fillers offer longer-lasting performance over NASHA-based dermal fillers in NLFs ," the authors write.

Explore further: Rarely 'too early' for appearance-enhancing procedures

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Rarely 'too early' for appearance-enhancing procedures

September 19, 2013
(HealthDay)—The effects of appearance-enhancing procedures such as neuromodulators, fillers, and light or laser treatments have lasting effects and can rarely be used "too early," according to a viewpoint piece published ...

Fractional, ablative er:YAG laser akin for skin resurfacing

November 10, 2012
(HealthDay)—Multiple sessions of fractional laser treatment with erbium:yttrium-aluminum-garnet (Er:YAG) for facial resurfacing are comparable to a single ablative Er:YAG laser treatment, according to a small study published ...

Cosmetic treatment can open the door to bacteria

March 11, 2014
Many people have 'fillers' injected into their facial tissue to give them 'bee-stung lips' or to smooth out their wrinkles. Unfortunately, a lot of cosmetic treatment customers experience unpleasant side effects in the form ...

Acellular dermal matrix safe, useful in breast reconstruction

June 2, 2012
(HealthDay) -- Acellular dermal matrices provide good outcomes for patients undergoing breast reconstruction following mastectomy, but the human AlloDerm matrix has a higher seroma rate than porcine Strattice matrix, according ...

Recommended for you

Novel approach to track HIV infection

August 18, 2017
Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions—infectious particles—to be connected to infectivity.

Faulty gene linked to obesity in adults

August 18, 2017
Groundbreaking new research linking obesity and metabolic dysfunction to a problem in the energy generators in cells has been published by researchers from the Harry Perkins Institute of Medical Research and The University ...

Two lung diseases killed 3.6 million in 2015: study

August 17, 2017
The two most common chronic lung diseases claimed 3.6 million lives worldwide in 2015, according to a tally published Thursday in The Lancet Respiratory Medicine.

New test differentiates between Lyme disease, similar illness

August 16, 2017
Lyme disease is the most commonly reported vector-borne illness in the United States. But it can be confused with similar conditions, including Southern Tick-Associated Rash Illness. A team of researchers led by Colorado ...

Addressing superbug resistance with phage therapy

August 16, 2017
International research involving a Monash biologist shows that bacteriophage therapy – a process whereby bacterial viruses attack and destroy specific strains of bacteria - can be used successfully to treat systemic, multidrug ...

Can previous exposure to west Nile alter the course of Zika?

August 15, 2017
West Nile virus is no stranger to the U.S.-Mexico border; thousands of people in the region have contracted the mosquito-borne virus in the past. But could this previous exposure affect how intensely Zika sickens someone ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.