Researchers identify predictors of awakening after acute coma

Researchers identify predictors of awakening after acute coma
For patients with acute coma, reversal and/or limitation of lateral brain displacement is associated with awakening, according to a study published online Jan. 27 in the Annals of Neurology.

(HealthDay)—For patients with acute coma, reversal and/or limitation of lateral brain displacement is associated with awakening, according to a study published online Jan. 27 in the Annals of Neurology.

Robert G. Kowalski, M.B.B.Ch., from the Johns Hopkins Hospital in Baltimore, and colleagues examined the correlation between lateral brain displacement and awakening from acute coma in a prospective observational study. The authors analyzed head computed tomography (CT) scans at coma onset, after awakening, and at follow-up in 85 patients with new-onset coma (mean age, 58 years).

The researchers found that, at coma onset, 51 percent of patients had midline shift on head CT and 51 percent of patients awakened. Younger age (odds ratio [OR], 1.039; P = 0.040), higher Glasgow Coma Scale score at coma onset (OR, 1.455; P = 0.001), non-traumatic coma etiology (OR, 4.464; P = 0.048), lesser pineal shift on follow-up CT (OR, 1.316; P = 0.009), and reduction or no increase in pineal shift on follow-up CT (OR, 11.628; P = 0.004) were independent predictors of awakening, in multivariate analysis.

"These findings suggest objective parameters to guide prognosis and treatment in patients with acute onset of ," the authors write.


Explore further

Personal View looks back on 40 years of the Glasgow Coma Scale

More information: Abstract
Full Text (subscription or payment may be required)
Journal information: Annals of Neurology

Copyright © 2015 HealthDay. All rights reserved.

Citation: Researchers identify predictors of awakening after acute coma (2015, February 5) retrieved 27 July 2021 from https://medicalxpress.com/news/2015-02-predictors-awakening-acute-coma.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
5 shares

Feedback to editors

User comments