Enhancing absorption and bioavailability of curcumin and turmeric

August 13, 2015, Taylor & Francis

Few natural products have demonstrated the range of protective and therapeutic promise as have turmeric and its principal bioactive components, the curcuminoids. Success in translating this potential into tangible benefits has been limited by inherently poor intestinal absorption, rapid metabolism, and limited systemic bioavailability. Seeking to overcome these limitations, food ingredient formulators have begun to employ a variety of approaches to enhance absorption and bioavailability.

The article "Beyond Yellow Curry: Assessing Commercial Curcumin Absorption Technologies," is now available from the Journal of the American College of Nutrition, official publication of the American College of Nutrition.

Turmeric and its main —curcumin, desmethoxycurcumin and bisdemethoxycurcumin—have many biological effects including anti-inflammatory, antioxidant, antitumor, antibacterial, and antiviral activities. Turmeric traditionally has been consumed in fat-based sauces, such as in a fat-rich yellow curry. More recently, intake of concentrated extracts of curcuminoids has become common in the form of health supplements. This review introduces needed order to the curcumin marketplace by examining studies on a number of commercial curcumin ingredients and evaluating them on a level playing field.

A hydrophilic carrier dispersed curcuminoid formula exhibits 45.9 times the bioavailability of the standard purified 95 percent curcuminoid preparation and, based on relative mass efficiency, 1.5 times the bioavailability of the next best commercial ingredient, a cyclodextrin complex.

Curcumin is currently being actively researched. When asked about the future of this field of research, author Dallas Clouatre said, "I would like to see and perhaps be involved in research on improving bioavailability. Also, it would be useful to test whether curcumin's benefits can be improved or even directed through use of combination products. The "silver bullet" research model for nutritional and pharmaceutical compounds long has been questioned. Alternatives, such as an examination of what is sometimes termed the "entourage effect," need to be explored."

The authors conclude, "Delivery strategies can significantly improve the bioavailability of curcuminoids. Total formula mass is important for making practical formulation decisions about dosing, cost and space."

Explore further: Cures and curcumin: Turmeric offers potential therapy for oral cancers

More information: "Beyond Yellow Curry: Assessing Commercial Curcumin Absorption Technologies." DOI: 10.1080/07315724.2014.950392

Related Stories

Cures and curcumin: Turmeric offers potential therapy for oral cancers

April 24, 2015
Turmeric—the familiar yellow spice common in Indian and Asian cooking—may play a therapeutic role in oral cancers associated with human papillomavirus, according to new research published in ecancermedicalscience.

Curcumin proved effective at combating cancer

March 16, 2015
WA scientists have helped re-affirm that curcumin, a chemical compound found in turmeric, is a safe and promising treatment for most cancers and other inflammation-driven diseases.

Spicy treatment the answer to aggressive cancer?

July 3, 2015
It has been treasured by food lovers for thousands of years for its rich golden colour, peppery flavour and mustardy aroma…and now turmeric may also have a role in fighting cancer.

Turmeric enhances mood in depression research trial

September 26, 2014
The antidepressant benefits of the Indian spice turmeric have been supported by the results of a trial run by a Murdoch University researcher.

Recommended for you

Marijuana use does not lower chances of getting pregnant

January 22, 2018
Marijuana use—by either men or women—does not appear to lower a couple's chances of getting pregnant, according to a new study led by Boston University School of Public Health (BUSPH) researchers.

Americans are getting more sleep

January 19, 2018
Although more than one in three Americans still don't get enough sleep, a new analysis shows first signs of success in the fight for more shut eye. According to data from 181,335 respondents aged 15 and older who participated ...

Wine is good for you—to a point

January 18, 2018
The Mediterranean diet has become synonymous with healthy eating, but there's one thing in it that stands out: It's cool to drink wine.

Sleep better, lose weight?

January 17, 2018
(HealthDay)—Sleeplessness could cost you when it's time to stand on your bathroom scale, a new British study suggests.

Who uses phone apps to track sleep habits? Mostly the healthy and wealthy in US

January 16, 2018
The profile of most Americans who use popular mobile phone apps that track sleep habits is that they are relatively affluent, claim to eat well, and say they are in good health, even if some of them tend to smoke.

Improvements in mortality rates are slowed by rise in obesity in the United States

January 15, 2018
With countless medical advances and efforts to curb smoking, one might expect that life expectancy in the United States would improve. Yet according to recent studies, there's been a reduction in the rate of improvement in ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.