Serious childhood infection tied to metabolic disease later in life

August 17, 2015
Serious childhood infection tied to metabolic disease later in life

(HealthDay)—Infection-related hospitalization (IRH) during childhood is independently associated with adverse adult metabolic variables, according to a study published online Aug. 17 in Pediatrics.

David P. Burgner, M.D., Ph.D., from the Murdoch Children's Research Institute in Parkville, Australia, and colleagues investigated whether hospitalization with childhood infection is associated with adult anthropometric and metabolic outcomes. The 1,376 participants (aged 3 to 9 years at baseline in 1980) had repeated assessments through childhood, adolescence, and adulthood (age 30 to 45 years in 2001 to 2011).

The researchers found that early-childhood IRH correlated with adverse adult, but not childhood, metabolic variables: increased (BMI; P = 0.02) and (risk ratio, 1.56; P = 0.03), when adjusting for age, gender, birth weight, childhood BMI and other risk factors, and family income. The age at which differences in adult BMI became persistent was related to age of IRH in childhood. Cases with more than one childhood IRH had the greatest increase in adult BMI.

"This finding suggests that infections and/or their treatment in may contribute to causal pathways leading to adult cardiometabolic diseases," the authors write.

Explore further: Patterns of childhood growth may trigger type 2 diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Patterns of childhood growth may trigger type 2 diabetes

February 21, 2015
(HealthDay)—Certain trajectories of body mass index (BMI) during childhood may increase risk of developing type 2 diabetes (T2D) later in life, according to research published online Feb. 14 in the Journal of Internal Medicine.

Childhood stress fuels weight gain in women

July 7, 2015
When it comes to weight gain for women, childhood stress appears to be a bigger culprit than stress during adulthood, finds a national study led by a Michigan State University sociologist.

Analysis examines genetic obesity susceptibility, association with body size in kids

October 20, 2014
A review of medical literature appears to confirm an association between genetic obesity susceptibility and postnatal gains in infant weight and length, as well as showing associations with both fat mass and lean mass in ...

Genetic evidence that body mass increases the risk of asthma in mid-childhood

July 1, 2014
Some of the increase in asthma risk toward the end of the 20th century could be attributed to the increase in body mass index (BMI) in mid-childhood, according to new research published in this week's PLOS Medicine. The study, ...

Childhood socioeconomic status affects brain volume

April 27, 2012
(HealthDay) -- Childhood socioeconomic status affects hippocampal volume in older adults, after adjusting for adult socioeconomic status, gender, education, and other factors, according to a study published in the May issue ...

Imaging study looks at brain effects of early adversity, mental health disorders

August 17, 2015
Adversity during the first six years of life was associated with higher levels of childhood internalizing symptoms, such as depression and anxiety, in a group of boys, as well as altered brain structure in late adolescence ...

Recommended for you

Stepfathers' 'Cinderella effect' challenged by new study

September 24, 2018
Long-held assumptions that stepfathers are far more likely to be responsible for child deaths than genetic parents have been challenged by researchers at the University of East Anglia (UEA).

Fatty acids can slow down an overheated immune system

September 21, 2018
Sometimes, the immune system mistakenly attacks the body's healthy tissue by responding to infections that do not exist. This causes chronic inflammation and leads to diseases including lupus (SLE), and this is what happens ...

Patient-centered visual aid helps physicians discuss risks, treatments with parents

September 21, 2018
A series of illustrations and charts designed as decision aids for parents of children with minor head injuries helped them communicate with emergency medicine physicians and make informed decisions about their child's care, ...

Study shows surprise low-level ozone impact on asthma patients

September 21, 2018
A new study led by UNC School of Medicine researchers indicates that ozone has a greater impact on asthma patients than previously thought. The study, published in the Journal of Allergy and Clinical Immunology, recruited ...

Fish-rich diets may boost babies' brain development

September 20, 2018
Women could enhance the development of their unborn child's eyesight and brain function by regularly eating fatty fish during pregnancy. This is the suggestion from a small-scale study led by Kirsi Laitinen of the University ...

Understanding epilepsy in pediatric tumors

September 20, 2018
Pediatric brain tumors are characterized by frequent complications due to intractable epilepsy compared to adult brain tumors. However, the genetic cause of refractory epilepsy in pediatric brain cancer has not been elucidated ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.