Serious childhood infection tied to metabolic disease later in life

August 17, 2015

Serious childhood infection tied to metabolic disease later in life
(HealthDay)—Infection-related hospitalization (IRH) during childhood is independently associated with adverse adult metabolic variables, according to a study published online Aug. 17 in Pediatrics.

David P. Burgner, M.D., Ph.D., from the Murdoch Children's Research Institute in Parkville, Australia, and colleagues investigated whether hospitalization with childhood infection is associated with adult anthropometric and metabolic outcomes. The 1,376 participants (aged 3 to 9 years at baseline in 1980) had repeated assessments through childhood, adolescence, and adulthood (age 30 to 45 years in 2001 to 2011).

The researchers found that early-childhood IRH correlated with adverse adult, but not childhood, metabolic variables: increased (BMI; P = 0.02) and (risk ratio, 1.56; P = 0.03), when adjusting for age, gender, birth weight, childhood BMI and other risk factors, and family income. The age at which differences in adult BMI became persistent was related to age of IRH in childhood. Cases with more than one childhood IRH had the greatest increase in adult BMI.

"This finding suggests that infections and/or their treatment in may contribute to causal pathways leading to adult cardiometabolic diseases," the authors write.

Explore further: Patterns of childhood growth may trigger type 2 diabetes

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Patterns of childhood growth may trigger type 2 diabetes

February 21, 2015
(HealthDay)—Certain trajectories of body mass index (BMI) during childhood may increase risk of developing type 2 diabetes (T2D) later in life, according to research published online Feb. 14 in the Journal of Internal Medicine.

Childhood stress fuels weight gain in women

July 7, 2015
When it comes to weight gain for women, childhood stress appears to be a bigger culprit than stress during adulthood, finds a national study led by a Michigan State University sociologist.

Analysis examines genetic obesity susceptibility, association with body size in kids

October 20, 2014
A review of medical literature appears to confirm an association between genetic obesity susceptibility and postnatal gains in infant weight and length, as well as showing associations with both fat mass and lean mass in ...

Genetic evidence that body mass increases the risk of asthma in mid-childhood

July 1, 2014
Some of the increase in asthma risk toward the end of the 20th century could be attributed to the increase in body mass index (BMI) in mid-childhood, according to new research published in this week's PLOS Medicine. The study, ...

Childhood socioeconomic status affects brain volume

April 27, 2012
(HealthDay) -- Childhood socioeconomic status affects hippocampal volume in older adults, after adjusting for adult socioeconomic status, gender, education, and other factors, according to a study published in the May issue ...

Imaging study looks at brain effects of early adversity, mental health disorders

August 17, 2015
Adversity during the first six years of life was associated with higher levels of childhood internalizing symptoms, such as depression and anxiety, in a group of boys, as well as altered brain structure in late adolescence ...

Recommended for you

Teens get more sleep with later school start time, researchers find

December 12, 2018
When Seattle Public Schools announced that it would reorganize school start times across the district for the fall of 2016, the massive undertaking took more than a year to deploy. Elementary schools started earlier, while ...

Study highlights potential benefits of continuous EEG monitoring for infant patients

December 12, 2018
A recent retrospective study evaluating continuous electroencephalography (cEEG) of children in intensive care units (ICUs) found a higher than anticipated number of seizures. The work also identified several conditions closely ...

Scientists have identified and modelled a distinct biology for paediatric AML

December 11, 2018
Scientists have identified and modelled a distinct biology for paediatric acute myeloid leukaemia, one of the major causes of death in children.

Expert proposes method to help premature infants thrive in the hospital

December 11, 2018
Even when they're not actively feeding, infants are perpetually sucking on toys, pacifiers, their own fingers—whatever they can get ahold of.

Heavy screen time appears to impact childrens' brains: study

December 10, 2018
Researchers have found "different patterns" in brain scans among children who record heavy smart device and video game use, according to initial data from a major ongoing US study.

Siblings of children with autism or ADHD are at elevated risk for both disorders

December 10, 2018
Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for both disorders, a new study led by Meghan Miller, assistant professor in the ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.