Hormone replacement therapy may benefit the kidneys

Hormone replacement therapy may help protect kidney health, according to a study that will be presented at ASN Kidney Week 2015 November 3-8 at the San Diego Convention Center in San Diego, CA.

The effect of on kidney function in postmenopausal women is unclear. To investigate, Andrea Kattah, MD, Vesna Garovic, MD (Mayo Clinic), and their colleagues studied 2217 postmenopausal women who participated in the Family Blood Pressure Program, a multi-network study aimed at analyzing the genetics of hypertension. A total of 673 women were taking hormone replacements and 1544 were not.

The researchers found that the prevalence of two markers of kidney disease—microalbuminuria and decreased estimated glomerular filtration rate—was significantly lower in women who were taking hormone replacement therapy as compared with women who were not. After adjusting for known risk factors for kidney and cardiovascular disease, the use of hormone replacement therapy remained significantly associated with lower levels of microalbuminuria.

"The risks and benefits of hormone replacement therapy in are still an area of active debate, and the effect of hormone replacement therapy on the kidney has shown variable results," said Dr. Kattah. "Clarifying the role of hormones on may have implications for explaining gender differences in chronic kidney disease, counseling women on the use of hormone replacement therapy, and future therapeutic targets for patients with ," said Dr. Kattah.


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Hormone replacement may protect women's kidneys, study suggests

More information: Study: "Hormone Replacement Therapy in Post-Menopausal Women is Associated with Better Kidney Function" (Abstract TH-PO577)
Citation: Hormone replacement therapy may benefit the kidneys (2015, November 5) retrieved 20 January 2021 from https://medicalxpress.com/news/2015-11-hormone-therapy-benefit-kidneys.html
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