Central venous pressure-guided hydration beneficial in CKD, CHF

Central venous pressure-guided hydration beneficial in CKD, CHF

(HealthDay)—For patients with chronic kidney disease (CKD) and congestive heart failure (CHF) undergoing coronary procedures, central venous pressure (CVP)-guided hydration is associated with reduced risk of contrast-induced nephropathy (CIN), according to a study published online Dec. 9 in JACC: Cardiovascular Interventions.

Geng Qian, M.D., from the Chinese People's Liberation Army General Hospital in Peking, and colleagues conducted a prospective comparative trial involving 264 patients with CKD and CHF undergoing coronary procedures. Patients were randomized to CVP-guided hydration or standard hydration (132 patients in each group). The hydration infusion rate was dynamically adjusted according to CVP level every hour in the CVP-guided group.

The researchers found that the total mean volume of isotonic saline administered was significantly higher in the CVP-guided hydration group than the (P < 0.001). CIN occurred less often in the CVP-guided hydration group (15.9 versus 29.5 percent in the control group; P = 0.006). There was no difference between the groups in the incidences of during the hydration (3.8 versus 3.0 percent; P = 0.500).

"CVP-guided fluid administration can safely and effectively reduce the risk of CIN in patients with CKD and CHF," the authors write.


Explore further

Hydration during PCI cuts risk of contrast-induced nephropathy

More information: Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2015 HealthDay. All rights reserved.

Citation: Central venous pressure-guided hydration beneficial in CKD, CHF (2015, December 11) retrieved 21 September 2019 from https://medicalxpress.com/news/2015-12-central-venous-pressure-guided-hydration-beneficial.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
1 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more