Early gestational diabetes tied to poor outcomes

Early gestational diabetes tied to poor outcomes

(HealthDay)—Diagnosis of gestational diabetes mellitus (GDM) early in pregnancy remains associated with poorer pregnancy outcomes, according to a study published online Dec. 8 in Diabetes Care.

Arianne N. Sweeting, Ph.D., from the Royal Prince Alfred Hospital in Sydney, and retrospectively evaluated outcomes for 4,873 women attending a university hospital antenatal diabetes clinic between 1991 and 2011. Women were classified as pre-existing diabetes (65 patients) or GDM diagnosed at <12 weeks of gestation (68 patients), at 12 to 23 weeks of gestation (1,247 patients), or at ≥24 weeks of gestation (3,493 patients).

The researchers found that women with pre-existing diabetes and early GDM had a higher prevalence of hypertensive disorders in pregnancy, including pre-eclampsia, preterm delivery, cesarean section, and neonatal jaundice (all P < 0.001). Rates of macrosomia (P = 0.8), large for gestational age (P = 0.4), and neonatal intensive care admission (P = 0.9) were comparable in women diagnosed with GDM at <12 weeks of gestation and with pre-existing diabetes.

"These findings indicate the need for further studies to establish the efficacy of alternative management approaches to improve outcomes in these high-risk pregnancies," the authors write.


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Citation: Early gestational diabetes tied to poor outcomes (2015, December 15) retrieved 19 January 2021 from https://medicalxpress.com/news/2015-12-early-gestational-diabetes-tied-poor.html
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