AAPM: intradiscal biacuplasty improves outcomes in LBP

February 24, 2016

(HealthDay)—For patients with chronic low back pain (LBP) of discogenic origin, 12-month outcomes are superior for intradiscal biacuplasty plus conservative medical management (IDB+CMM) versus CMM alone, according to a study presented at the annual meeting of the American Academy of Pain Medicine, held from Feb. 18 to 21 in Palm Springs, Calif.

Michael Gofeld, M.D., from the University of Toronto, and colleagues examined the 12-month outcomes for patients with chronic LBP of discogenic origin treated with IDB+CMM. Sixty-three patients were randomized to receive IDB+CMM (29 patients) or CMM alone (34 patients). At six months post randomization, CMM-alone participants were allowed to cross over to IDB+CMM (25 ).

The researchers found that for the original IDB+CMM group, the mean outcome measures were each statistically and clinically superior to baseline values at 12 months. At 12 months, a minimum of 50 percent of the IDB+CMM group reported a continued response to treatment. The IDB+CMM group experienced a mean visual analog scale change of −2.2 from baseline, 14-point decrease in Oswestry Disability Index from baseline, 1.7-point improvement in patient global impression of change, and 0.13-point improvement in quality of life index. At six months, crossover subjects responded similarly to the originally treated group.

"The results were not only statistically significant but—more importantly—clinically meaningful," Gofeld said in a statement. "Without addressing disc pathology, and function do not get better."

Explore further: Baseline pain severity predicts worse long-term LBP outcomes

More information: Press Release
More Information

Related Stories

Baseline pain severity predicts worse long-term LBP outcomes

August 23, 2013
(HealthDay)—Patients' baseline pain and the perception that their pain will persist are significant predictors of poor outcomes for low back pain (LBP) over the short and long term, according to a study published in the ...

Benefit of early physical therapy for low-back pain appears modest

October 13, 2015
Early physical therapy for recent-onset low back pain resulted in statistically significant improvement in disability compared to usual care, but the improvement was modest and did not achieve a difference considered clinically ...

Surgery found to be marginally better for discogenic pain

December 14, 2013
(HealthDay)—Surgical patients demonstrate greater improvement at one year compared to patients utilizing nonsurgical treatment for discogenic pain, although success rates for either group are only fair, according to a study ...

Muscle relaxant or opioid combined with NSAID does not improve low back pain

October 20, 2015
Among patients with acute, low back pain presenting to an emergency department, neither the nonsteroidal anti-inflammatory drug (NSAID) naproxen combined with oxycodone/acetaminophen or the muscle relaxant cyclobenzaprine ...

AAPM: Platelet-rich plasma offers short-term benefit

March 31, 2015
(HealthDay)—For patients with facet joint arthropathy, platelet-rich plasma (PRP) has a short-term positive impact, according to a study presented at the annual meeting of the American Academy of Pain Medicine, held from ...

Spanish registry IDs predictors of low back pain improvement

December 20, 2012
(HealthDay)—For patients with acute or chronic low back pain (LBP), predictors have been identified for clinically relevant improvements in LBP, pain down the leg (LP), and disability at three months, according to research ...

Recommended for you

Rhesus macaque model offers route to study Zika brain pathology

June 21, 2018
Rhesus macaque monkeys infected in utero with Zika virus develop similar brain pathology to human infants, according to a report by researchers at the California National Primate Research Center and School of Veterinary Medicine ...

Breakthrough treatment for crippling jaw disease created

June 20, 2018
A first-ever tissue implant to safely treat a common jaw defect, known as temporomandibular joint dysfunction, has been successfully tested by UCI-led researchers in a large animal model, according to new findings.

Cell-free DNA profiling informative way to monitor urinary tract infections

June 20, 2018
Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections (UTIs) that surpasses traditional methods in providing valuable information about the dynamics ...

New flu vaccine only a little better than traditional shot

June 20, 2018
A newer kind of flu vaccine only worked a little bit better in seniors this past winter than traditional shots, the government reported Wednesday.

Blood signature could improve early tuberculosis diagnosis

June 19, 2018
A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin. Such a signature has now been developed by a team led by the Francis Crick ...

Scientists uncover a factor important for Zika virus host species restriction

June 19, 2018
Princeton University researchers Qiang Ding, Alexander Ploss, and colleagues have identified one of the mechanisms by which Zika virus (ZIKV) circumvents immune control to replicate in human cells. The paper detailing this ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.