Heart arrhythmia drug may fight plaque buildup in blood vessels

Human heart. Credit: copyright American Heart Association

New research in mice provides convincing evidence that digoxin, a drug prescribed to treat atrial fibrillation, can help protect against atherosclerosis.

Investigators found that decreased the levels of total cholesterol, triglycerides and LDL-cholesterol by 41%, 54%, and 20%, respectively, in mice treated with high-dose digoxin compared with control mice.

The findings are published in the British Journal of Pharmacology.

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More information: Huairui Shi et al. Digoxin reduces atherosclerosis in apolipoprotein E-deficient mice, British Journal of Pharmacology (2016). DOI: 10.1111/bph.13453
Journal information: British Journal of Pharmacology

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Citation: Heart arrhythmia drug may fight plaque buildup in blood vessels (2016, February 17) retrieved 11 December 2019 from https://medicalxpress.com/news/2016-02-heart-arrhythmia-drug-plaque-buildup.html
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