Late reactions in food challenges common

Late reactions in food challenges common

(HealthDay)—Late reactions in children undergoing food challenges are common and poorly predicted but generally not severe, according to a study published online May 10 in Allergy.

Jacquelien Saleh-Langenberg, from the University of Groningen in the Netherlands, and colleagues sought to determine the prevalence, severity, and clinical characteristics of late reactions in food-allergic and adolescents after a double-blind, placebo-controlled food challenge (DBPCFC) in 1,142 children.

The researchers found that there were late reactions in 400 child-test combinations. These late reactions were poorly predictable and generally not severe. Younger children reported more late reactions, including those on the placebo day.

"Children who do not experience severe immediate reactions may be safely discharged home two hours after a DBPCFC," the authors write.

Explore further

Profilin can induce severe food-allergic reactions

More information: Abstract
Full Text (subscription or payment may be required)
Journal information: Allergy

Copyright © 2016 HealthDay. All rights reserved.

Citation: Late reactions in food challenges common (2016, May 11) retrieved 26 July 2021 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments