Biomarkers to assess degree of brain injury in postconcussion syndrome

A new study published online by JAMA Neurology included 16 professional Swedish hockey players and examined whether persistent symptoms after mild traumatic brain injury were associated with brain injury as evaluated by cerebrospinal fluid biomarkers for axonal damage and other aspects of central nervous system injury.

The had prolonged postconcussion symptoms for more than three months, according to the article by Kaj Blennow, M.D., Ph.D., of the Sahlgrenska University Hospital, Sweden, and coauthors. The study also included 15 neurologically healthy control patients.

Authors reported increased cerebrospinal fluid neurofilament light protein and reduced amyloid β levels in hockey players with repeated mild and PCS [postconcussion syndrome], findings that suggest evidence of white matter injury and amyloid deposition.

"Measurement of these biomarkers may be an objective tool to assess the degree of central nervous system injury in individuals with PCS and to distinguish individuals who are at risk of developing ," the report concludes.


Explore further

CDC study identifies patients with mild traumatic brain injury at increased risk of PTSD

More information: JAMA Neurol. Published online September 19, 2016. DOI: 10.1001/jamaneurol.2016.2038
Journal information: Archives of Neurology

Citation: Biomarkers to assess degree of brain injury in postconcussion syndrome (2016, September 19) retrieved 20 January 2020 from https://medicalxpress.com/news/2016-09-biomarkers-degree-brain-injury-postconcussion.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
2 shares

Feedback to editors

User comments