Advantages of FIT as CRC screening method discussed

October 25, 2016

(HealthDay)—Fecal immunochemical testing (FIT) has advantages as a colorectal cancer (CRC) screening method, and should be a component of a screening program, according to an Ideas and Opinions piece published online Oct. 25 in the Annals of Internal Medicine.

In light of recent findings questioning the effectiveness of colonoscopy, David S. Weinberg, M.D., from the Fox Chase Cancer Center in Philadelphia, and colleagues discussed CRC screening methods.

The researchers note that a U.S. Multi-Society Task Force recently released an examination of the evidence relating to use of FIT for CRC screening, emphasizing the advantages of FIT over guaiac-based fecal occult blood testing. Advantages include higher sensitivity while maintaining similar specificity; more consistent detection of advanced adenomas; and patient preference for FIT. Recent studies show that FIT-based screening yields a reduction in CRC incidence similar to that of colonoscopy when adherence to serial completion is high, and patients are more likely to choose FIT over colonoscopy; consequently, more cancers (but fewer advanced adenomas) could be detected with FIT screening. Practical concerns surround implementation of annual FIT screening; for example, a large-scale FIT screening would require efficient tracking mechanisms.

"For primary care and other clinicians who provide CRC screening services, this authoritative consensus statement offers strong evidence for FIT as an excellent alternative for CRC prevention," the authors write.

Explore further: Study: Colonoscopy after 75 may not be worth it

More information: Full Text (subscription or payment may be required)

Related Stories

Study: Colonoscopy after 75 may not be worth it

September 26, 2016
(HealthDay)—A colonoscopy can find and remove cancerous growths in the colon, but it may not provide much cancer prevention benefit after the age of 75, a new study suggests.

Support for fecal testing in familial colorectal cancer screening

October 29, 2014
Fecal immunochemical tests (FIT) may be as effective as colonoscopies when it comes to detecting colorectal cancer among first-degree relatives of patients with colorectal cancer, according to a new study in Gastroenterology, ...

Hybrid screening strategy emerges for colorectal cancer

August 27, 2013
A strategy that combines two effective colorectal cancer screening methods, fecal immunological test and colonoscopy, may improve prevention and detection of colorectal cancer and reduce costs, according to a new study in ...

Colonoscopy is indicated in unscreened elderly patients

June 3, 2014
(HealthDay)—Colorectal cancer (CRC) screening should be considered as a cost-effective strategy in unscreened patients older than 75 years, according to research published in the June 3 issue of the Annals of Internal Medicine.

Cancers caught during screening colonoscopy are more survivable

July 13, 2015
Patients whose colorectal cancer (CRC) is detected during a screening colonoscopy are likely to survive longer than those who wait until they have symptoms before having the test, according to a study in the July issue of ...

Study finds stool test effective for detecting colon cancer

January 26, 2016
(HealthDay)—Tests for blood in the stool can consistently detect colon cancer when used on an annual basis, and they are effective even in the second, third and fourth years of screening, a new study says.

Recommended for you

Mutant cells colonize our tissues over our lifetime

October 18, 2018
By the time we reach middle age, more than half of the oesophagus in healthy people has been taken over by cells carrying mutations in cancer genes, scientists have uncovered. By studying normal oesophagus tissue, scientists ...

Study involving hundreds of patient samples may reveal new treatment options of leukemia

October 17, 2018
After more than five years and 672 patient samples, an OHSU research team has published the largest cancer dataset of its kind for a form of leukemia. The study, "Functional Genomic Landscape of Acute Myeloid Leukemia", published ...

A 150-year-old drug might improve radiation therapy for cancer

October 17, 2018
A drug first identified 150 years ago and used as a smooth-muscle relaxant might make tumors more sensitive to radiation therapy, according to a recent study led by researchers at The Ohio State University Comprehensive Cancer ...

Loss of protein p53 helps cancer cells multiply in 'unfavourable' conditions

October 17, 2018
Researchers have discovered a novel consequence of loss of the tumour protein p53 that promotes cancer development, according to new findings in eLife.

Researcher fighting breast cancer with light therapy

October 17, 2018
When treatment is working for a patient who is fighting cancer, the light at the end of the tunnel is easier to see.

New method uses just a drop of blood to monitor lung cancer treatment

October 17, 2018
Dr. Tasuku Honjo won the 2018 Nobel Prize in physiology or medicine for discovering the immune T-cell protein PD-1. This discovery led to a set of anti-cancer medications called checkpoint inhibitors, one of the first of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.