Non-medical causes responsible for many maternal deaths

October 13, 2016, Boston University Medical Center

Intimate partner violence, substance use disorder and mental illness may be as threatening to health and survival during pregnancy in U.S cities as medical issues.

The findings, which appear online in the American Journal of Public Health, suggest that public health programs and health systems could more effectively prevent by addressing psychosocial contributors to health when pregnant women present for care.

Maternal mortality rates are increasing in the U.S. and include deaths due to medical causes thought to be directly related to pregnancy, such as hemorrhage, thromboembolism and hypertensive disease. Although substance use, serious mental illness and IPV may also be exacerbated by pregnancy and are known to worsen perinatal outcomes, deaths specifically due to these causes are not included in current definitions of U.S. maternal mortality.

Rather than focusing on maternal mortality cases alone, researchers reviewed cases of all women who died during or within a year of pregnancy in Philadelphia from 2010 to 2014. They extracted cause of death, contributing factors and any recorded history of health care use from the case summaries created by the medical examiner's office. They found that approximately half (42 of 85) of pregnancy-associated deaths were from unintentional injuries, homicide or suicide. Drug overdose was the leading cause of death and substance use was noted during or around events leading to death in almost half of non-overdose deaths. A history of serious mental illness was found in more than a third of non-suicide deaths. And a history of was documented in 15 of 77 non-homicide deaths. Regardless of cause of death, nearly half of all decedents had an unscheduled hospital visit documented within a month of their death, suggesting missed opportunities to intervene in these deaths.

"Our analysis used a broader framework than traditional studies of death during pregnancy and found that a narrow focus on the medical causes of maternal mortality may be inadequate. Even women who died from medical causes frequently had histories of , serious mental illness or partner violence—hidden potential contributors to ," explained lead author Pooja Mehta, MD, MSHP, assistant professor of obstetrics & gynecology at Boston University School of Medicine.

Traditionally, public health and physician efforts to make pregnancy safer have focused on medical causes, for example, the prevention of excessive bleeding, blood clots, high blood pressure and heart disease. "An approach that relies on a broader framework to define the "preventable" pregnancy-associated and leverage health system contacts to address and social context is vital to addressing the U.S. maternal health crisis," said Mehta, a practicing obstetrician-gynecologist and health policy researcher at Boston Medical Center.

The researchers believe there are missed opportunities to intervene on behalf of those who are struggling during pregnancy, not just on Labor and Delivery, but also in emergency rooms, triage settings and in the community. "Out-of-the-box strategies such as shifting resources, screening and support to these other settings may be important for pregnant people at risk for poor outcomes who turn to the health system for a helping hand," she added.

Explore further: Research finds maternal death rate increasing in U.S.

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