Vitamin D doesn't improve glucose measures

Vitamin D doesn't improve glucose measures

(HealthDay)—Weekly doses of vitamin D do not improve oral glucose tolerance or markers of glycemic status among those at risk for diabetes, according to a study published online Sept. 26 in Diabetes, Obesity and Metabolism.

Tracy S. Moreira-Lucas, Ph.D., from the University of Toronto, and colleagues conducted a 24-week randomized, placebo-controlled trial to study the effect of 28,000 IU of vitamin D3 once weekly on after a two-hour, 75-g oral glucose tolerance test (2hrPC glucose); ; and beta-cell function. Of 71 participants with serum 5-hydroxyvitamin-D (25[OH]D) ≤65 nmol/L, impaired fasting glucose, and elevated glycated hemoglobin, 35 subjects received vitamin D and 36 received placebo.

The researchers found that serum 25(OH)D significantly increased in the vitamin D group. However, no significant differences in fasting or 2hPC glucose or other indices of , including beta-cell function and insulin sensitivity, were seen. The results were similar in a subgroup analysis of individuals with 25(OH)D <50nmol/L and prediabetes. The vitamin D group did show a significant reduction in low-density lipoprotein cholesterol.

"Weekly doses of vitamin D3 in individuals with sub-optimal vitamin D and at risk for type 2 diabetes did not improve or markers of glycemic status," the authors write.


Explore further

SFRP4 linked to impaired glucose tolerance, T2DM

More information: Abstract
Full Text (subscription or payment may be required)

Copyright © 2016 HealthDay. All rights reserved.

Citation: Vitamin D doesn't improve glucose measures (2016, October 5) retrieved 18 January 2020 from https://medicalxpress.com/news/2016-10-vitamin-d-doesnt-glucose.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments