DASH diet reduces serum uric acid in prehypertension

December 5, 2016

(HealthDay)—Among adults with prehypertension or stage I hypertension, following the Dietary Approaches to Stop Hypertension (DASH) diet lowers serum uric acid (UA), according to a study published online Nov. 28 in Arthritis & Rheumatology.

Stephen P. Juraschek, M.D., Ph.D., from Johns Hopkins University in Baltimore, and colleagues conducted an ancillary study of a randomized crossover feeding trial in 103 adults with prehypertension or stage I hypertension. Participants were randomized to receive either the DASH diet or a control diet that was typical of an average American diet. They were further fed low, medium, and high levels of sodium for 30 days. At baseline and following each feeding period, UA level were measured.

The researchers found that serum UA was reduced with the DASH diet (−0.35 mg/dL), with a higher effect for those with a baseline serum UA level of ≥7 mg/dL (−1.29 mg/dL). Increasing from the low level correlated with a reduction in serum UA during the medium and the high sodium intake periods (−0.3 and −0.4 mg/dL, respectively; both P < 0.001).

"The DASH diet lowered serum UA, and this effect was greater among participants with hyperuricemia," the authors write. "Moreover, we found that higher sodium intake decreased serum UA, which enhances our knowledge of urate pathophysiology and risk factors for hyperuricemia."

Several food companies donated food, and a food storage company provided food storage.

Explore further: Blood pressure diet may help prevent gout flares

More information: Full Text

Related Stories

Blood pressure diet may help prevent gout flares

August 15, 2016
New research indicates that a healthy diet can effectively lower blood levels of uric acid, a known trigger of gout. The findings are published in Arthritis & Rheumatology, a journal of the American College of Rheumatology ...

Study finds higher fat variation of DASH diet lowers blood pressure, triglycerides

January 11, 2016
The Dietary Approaches to Stop Hypertension (DASH) dietary pattern, which is high in fruits, vegetables and low fat dairy foods, significantly lowers blood pressure as well as low-density lipoprotein cholesterol (LDL-C) and ...

Low-normal sodium deemed major risk for mortality in elderly

March 25, 2016
A slightly lower serum sodium concentration within the normal range is a major risk factor for mortality in elderly adults, according to a study published in the March issue of the Journal of the American Geriatrics Society.

Diet designed to lower blood pressure also reduces risk of kidney disease

August 9, 2016
People who ate a diet high in nuts and legumes, low-fat dairy, whole grains, fruits, and vegetables and low in red and processed meat, sugar-sweetened beverages and sodium were at a significantly lower risk of developing ...

Diet rich in unsaturated fat may up insulin sensitivity

June 14, 2013
(HealthDay)—A diet rich in unsaturated fat may increase insulin sensitivity in individuals who are at higher risk for cardiovascular disease, according to research published in the May issue of Diabetes Care.

Salt and sodium intake remains high in China

February 16, 2016
Yongning Wu, Ph.D., of the China National Centre for Food Safety Risk Assessment, Beijing, China, and colleagues compared salt and sodium consumption in China in 2000 with 2009-2012. The study appears in the February 16 issue ...

Recommended for you

Scientists find key proteins control risk of osteoarthritis during aging

February 14, 2018
More than 30 million Americans suffer from osteoarthritis making it one of the most common age-related diseases.

Acute treatment suppresses posttraumatic arthritis in ankle injury

February 7, 2018
A University of Iowa study has identified a method for inhibiting the occurrence of an aggressive form of arthritis that frequently develops following a severe traumatic injury. The preclinical work demonstrates the potential ...

Small molecule could make a big difference for arthritis patients

February 7, 2018
Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

Study finds bacteria in milk linked to rheumatoid arthritis

January 30, 2018
A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida.

Osteoarthritis could be treated as two diseases, scientists reveal

January 10, 2018
Scientists at The University of Manchester have discovered that most people with osteoarthritis can be subdivided into two distinct disease groups, with implications for diagnosis and drug development.

US arthritis prevalence is much higher than current estimates

November 27, 2017
New research indicates that the prevalence of arthritis in the United States has been substantially underestimated, especially among adults

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.