Endoscopic sleeve gastroplasty offers option for select patients

December 20, 2016

(HealthDay)—The minimally invasive procedure endoscopic sleeve gastroplasty (ESG) delays gastric emptying, induces early satiation, and successfully results in weight loss, according to a study published in the January issue of Clinical Gastroenterology and Hepatology.

Barham K. Abu Dayyeh, M.D., M.P.H., from the Mayo Clinic in Rochester, Minn., and colleagues examined the durability and effects of ESG on and gastrointestinal function in a prospective study. Twenty-five obese individuals underwent ESG from September 2012 through March 2015; they were followed for a median of nine months.

The researchers found that at six, nine, 12, and 20 months after the procedure, subjects had lost 53 ± 17 percent, 56 ± 23 percent, 54 ± 40 percent, and 45 ± 41 percent of , respectively (P < 0.01). At three months, endoscopy revealed intact gastroplasty in all subjects. Physiological analyses of four patients after ESG showed a 59 percent decrease in caloric consumption to reach maximum fullness (P = 0.003), slowing of gastric emptying of solids (P = 0.03), and a trend toward increased insulin sensitivity (P = 0.06). Serious were observed in three patients (perigastric inflammatory collection, pulmonary embolism, and small pneumothorax); they made full recoveries without the need for surgical interventions. After the technique was adjusted there were no further serious adverse events.

"ESG delays gastric emptying, induces early satiation, and significantly reduces body weight," the authors write. "ESG could be an alternative to bariatric surgery for selected patients with obesity."

Two authors disclosed financial ties to Apollo Endosurgery, which partially funded the study.

Explore further: Endoscopic sleeve gastroplasty: A promising new weight loss procedure

More information: Full Text

Related Stories

Endoscopic sleeve gastroplasty: A promising new weight loss procedure

January 20, 2016
In the fight against obesity, bariatric surgery is currently the most effective treatment; however, only 1 to 2 percent of qualified patients receive this surgery due to limited access, patient choice, associated risks and ...

New type of weight-loss surgery may be less risky, cheaper

February 15, 2016
(HealthDay)—A new type of weight-loss procedure offers an alternative to traditional bariatric surgery for people who are mildly to moderately obese, researchers report.

Rapid improvement in insulin sensitivity with bariatric surgery

September 5, 2016
(HealthDay)—For obese patients without diabetes, bariatric surgery improves insulin sensitivity (IS), with more pronounced improvements for Roux-en-Y gastric bypass (RYGB) than for laparoscopic adjustable gastric banding ...

Metabolic benefit same with similar weight loss after surgery

November 21, 2016
(HealthDay)—Early metabolic differences following laparoscopic adjustable gastric banding (LAGB) and Roux-en-Y gastric bypass (RYGB) in obese individuals with type 2 diabetes mellitus (T2DM) disappear when weight loss reaches ...

Relamorelin beneficial in adults with diabetic gastroparesis

July 7, 2016
(HealthDay)—For adults with diabetic gastroparesis, relamorelin reduces vomiting frequency and severity and accelerates gastric emptying, according to a study published in the July issue of Gastroenterology.

In mildly obese patients, sleeve-it surgery may increase weight loss and glycemic control

April 1, 2016
In mildly obese ("class I") patients, sleeve with ileal transposition (sleeve-IT) surgery results in better glycemic control than either gastric bypass or clinical treatment, a new study from Brazil suggests. The results ...

Recommended for you

Cold open water plunge provides instant pain relief

February 12, 2018
A short, sharp, cold water swim may offer an alternative to strong painkillers and physiotherapy to relieve severe persistent pain after surgery, suggest doctors in the journal BMJ Case Reports.

Study spotlights risks in anesthesiologist handoffs

February 9, 2018
Most patients are totally unaware that the anesthesiologist who put them under for surgery might not be the same one who brings them out even though that 'handoff' between the two doctors has been linked to a series of negative ...

One in five older adults experience brain network weakening following knee replacement surgery

February 7, 2018
A new University of Florida study finds that 23 percent of adults age 60 and older who underwent a total knee replacement experienced a decline in activity in at least one region of the brain responsible for specific cognitive ...

New algorithm decodes spine oncology treatment

February 6, 2018
Every kind of cancer can spread to the spine, yet two physician-scientists who treat these patients describe a paucity of guidance for effectively providing care and minimizing pain.

Patients and doctors often disagree in evaluation of surgical scarring

February 1, 2018
When it comes to the physical scars surgery leaves behind, a new study shows patients and doctors often don't assess their severity the same way. Researchers from the Perelman School of Medicine at the University of Pennsylvania ...

Boosting a key protein to help bones that won't heal

February 1, 2018
When a patient breaks a bone, there's a possibility the fracture won't heal properly or quickly—even with the aid of pins, plates or a cast.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.