Type of treatment impacts recurrence in laryngeal SCC

December 14, 2016

(HealthDay)—For patients with laryngeal squamous cell carcinoma (SCC), factors predictive of recurrence include neck metastasis at presentation and nonsurgical treatment, according to a study published online Nov. 30 in Head & Neck.

Aaro Haapaniemi, M.D., from Helsinki University Hospital in Finland, and colleagues analyzed a nationwide laryngeal SCC cohort from Finnish university hospitals during 2001 to 2005. Data were included for 316 patients with initial successful therapy.

The researchers found that 22 percent of patients had laryngeal SCC . The median time to recurrence was nine months, and 90 percent occurred within 36 months following treatment. Independent prognostic factors for recurrence included the World Health Organization performance status >0, neck metastasis at presentation, and . Five-year overall survival was 53 percent for patients with local recurrence and 5 percent for patients with regional/distant recurrences. For glottic and nonglottic laryngeal SCC recurrence, overall survival was 45 and 0 percent, respectively.

"The type of treatment affected the risk of recurrence in this retrospective series. Local recurrences carried a chance for successful salvage ," the authors write. "Routine follow-up beyond 36 months remains controversial."

Explore further: Factors ID'd for recurrence after radical cystectomy

More information: Full Text (subscription or payment may be required)

Related Stories

Factors ID'd for recurrence after radical cystectomy

October 25, 2016

(HealthDay)—For patients undergoing robot-assisted radical cystectomy, predictors of recurrence include mainly tumor characteristics, according to a study published in the October issue of The Journal of Urology.

Fluorescence visualization-guided Sx efficacious in oral CA

January 20, 2016

(HealthDay)—For patients with oral cancer, fluorescence visualization (FV)-guided surgery is associated with a reduction in local recurrence, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck ...

No specific findings to ID recurrence in head and neck CA

September 26, 2015

(HealthDay)—For patients treated for head and neck squamous cell carcinoma (HNSCC), no definite index of symptoms or signs indicates local recurrence or second primary malignancy, according to a study published online Sept. ...

Recommended for you

Researchers identify new target for cancer immunotherapy

January 17, 2017

Massachusetts General Hospital investigators have found new evidence that the tumor necrosis factor receptor type II (TNFR2) may be a major target for immuno-oncology treatments, which induce a patient's immune system to ...

Study reveals why cancer cells spread within the body

January 17, 2017

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.