Type of treatment impacts recurrence in laryngeal SCC

December 14, 2016

(HealthDay)—For patients with laryngeal squamous cell carcinoma (SCC), factors predictive of recurrence include neck metastasis at presentation and nonsurgical treatment, according to a study published online Nov. 30 in Head & Neck.

Aaro Haapaniemi, M.D., from Helsinki University Hospital in Finland, and colleagues analyzed a nationwide laryngeal SCC cohort from Finnish university hospitals during 2001 to 2005. Data were included for 316 patients with initial successful therapy.

The researchers found that 22 percent of patients had laryngeal SCC . The median time to recurrence was nine months, and 90 percent occurred within 36 months following treatment. Independent prognostic factors for recurrence included the World Health Organization performance status >0, neck metastasis at presentation, and . Five-year overall survival was 53 percent for patients with local recurrence and 5 percent for patients with regional/distant recurrences. For glottic and nonglottic laryngeal SCC recurrence, overall survival was 45 and 0 percent, respectively.

"The type of treatment affected the risk of recurrence in this retrospective series. Local recurrences carried a chance for successful salvage ," the authors write. "Routine follow-up beyond 36 months remains controversial."

Explore further: Factors ID'd for recurrence after radical cystectomy

More information: Full Text (subscription or payment may be required)

Related Stories

Factors ID'd for recurrence after radical cystectomy

October 25, 2016
(HealthDay)—For patients undergoing robot-assisted radical cystectomy, predictors of recurrence include mainly tumor characteristics, according to a study published in the October issue of The Journal of Urology.

Excision margins don't impact melanoma recurrence, survival

April 12, 2016
(HealthDay)—Wider excision margins in thick cutaneous melanoma cases do not improve locoregional recurrence or melanoma-specific survival (MSS), according to research published online March 25 in Head & Neck.

Fluorescence visualization-guided Sx efficacious in oral CA

January 20, 2016
(HealthDay)—For patients with oral cancer, fluorescence visualization (FV)-guided surgery is associated with a reduction in local recurrence, according to a study published online Jan. 14 in JAMA Otolaryngology-Head & Neck ...

No specific findings to ID recurrence in head and neck CA

September 26, 2015
(HealthDay)—For patients treated for head and neck squamous cell carcinoma (HNSCC), no definite index of symptoms or signs indicates local recurrence or second primary malignancy, according to a study published online Sept. ...

Staged surgical excision superior for treatment of lentigo maligna

December 9, 2015
(HealthDay)—For patients with lentigo maligna, staged surgical excision is associated with a low rate of recurrence, according to research published online Nov. 30 in the British Journal of Dermatology.

Recommended for you

Single blood test screens for eight cancer types

January 18, 2018
Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

How cancer metastasis happens: Researchers reveal a key mechanism

January 18, 2018
Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...

These foods may up your odds for colon cancer

January 18, 2018
(HealthDay)—Chowing down on red meat, white bread and sugar-laden drinks might increase your long-term risk of colon cancer, a new study suggests.

The pill lowers ovarian cancer risk, even for smokers

January 18, 2018
(HealthDay)—It's known that use of the birth control pill is tied to lower odds for ovarian cancer, but new research shows the benefit extends to smokers or women who are obese.

Researchers find a way to 'starve' cancer

January 18, 2018
Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital ...

Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy

January 18, 2018
Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists from the German Cancer Research ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.