Optimized treatment relieves pain in chronic pancreatitis

January 10, 2017

(HealthDay)—For most patients with chronic pancreatitis (CP), optimized medical and interventional treatment is associated with significant pain relief, according to a study published online Jan. 4 in the Journal of Gastroenterology and Hepatology.

For the study, researchers from the All India Institute of Medical Sciences in New Delhi enrolled 313 consecutive with CP (92 percent with abdominal pain) who were treated with a well-balanced diet, pancreatic enzymes, and antioxidants. If failed, patients were offered endoscopic therapy and/or surgery.

The researchers found that the etiology of CP was idiopathic in 71.6 percent of the patients and alcohol in 26.2 percent. Significant pain relief was achieved at one-year follow-up in 84.7 percent of patients: 52.1, 16.7, 7.6, and 8.3 percent, respectively, with medical therapy, , surgery, and spontaneously. There was a significant decrease in the mean pain score, from 6.36 ± 1.92 to 1.62 ± 2.1. Among the 261, 218, 112, and 51 patients with followed up for three, five, 10, and 15 years, 54, 57.3, 60.7, and 68.8 percent, respectively, became pain-free at follow-up.

"Significant pain relief is achieved in the majority of patients with optimized medical and interventional treatment," the authors write.

Explore further: Antioxidant-pregabalin cuts pain in chronic calcific pancreatitis

More information: Full Text

Related Stories

Antioxidant-pregabalin cuts pain in chronic calcific pancreatitis

March 14, 2016
(HealthDay)—For patients with chronic calcific pancreatitis (CCP), antioxidant-pregabalin combination is associated with significant pain reduction, according to a study published online March 6 in the Journal of Gastroenterology ...

Endoscopic therapy is an effective treatment for chronic pancreatitis

July 16, 2012
(Medical Xpress) -- Endoscopic therapy was found to be effective for patients with chronic pancreatitis, according to researchers at the University of Pittsburgh School of Medicine, whose findings appear in the July issue ...

High-frequency spinal cord stimulation provides better results in chronic back and leg pain

October 28, 2016
For patients with severe, chronic back and leg pain, a new high-frequency spinal cord stimulation (SCS) technique provides superior clinical outcomes, compared to conventional low-frequency SCS, reports a clinical trial in ...

New therapy delivers long-term relief for chronic back, leg pain, study finds

July 28, 2015
Chronic back and leg pain sufferers in search of better pain relief options may have a new choice. According to a study published in the Online First edition of Anesthesiology, the official medical journal of the American ...

Pain and itch highly prevalent months after herpes zoster

September 14, 2016
(HealthDay)—For patients with herpes zoster (HZ), pain and itch are prevalent and pain is associated with quality of life and increased costs, according to a study published online Sept. 9 in Pain Practice.

Recommended for you

Screening could catch a quarter of hip fractures before they happen

December 15, 2017
Community screening for osteoporosis could prevent more than a quarter of hip fractures in older women - according to new research led by the University of East Anglia (UEA).

New cellular approach found to control progression of chronic kidney disease

December 15, 2017
Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage ...

Testing shows differences in efficacy of Zika vaccines after one year

December 15, 2017
(Medical Xpress)—A large team of researchers with members from Harvard Medical School, Walter Reed Army Institute of Research, Bioqual Inc. and MIT has found that the efficacy of the three types of Zika vaccines currently ...

How to regulate fecal microbiota transplants

December 15, 2017
(Medical Xpress)—A small team of researchers at the University of Maryland, some with affiliations to the Veterans Affairs Maryland Health Care System, has written and published a Policy Forum piece in the journal Science ...

Urine test developed to test for tuberculosis

December 14, 2017
(Medical Xpress)—An international team of researchers has developed a urine test that can be used to detect tuberculosis (TB) in human patients. In their paper published in Science Translational Medicine, the group describes ...

40 years after first Ebola outbreak, survivors show signs they can stave off new infection

December 14, 2017
Survivors of the first known Ebola outbreak, which occurred in the Democratic Republic of the Congo in 1976, may be key to development of vaccines and therapeutic drugs to treat future outbreaks, according to a new study ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.