Cutaneous malignancies can mimic seborrheic keratosis

June 15, 2017

(HealthDay)—Of a sample of lesions deemed seborrheic keratoses clinically, 3.1 percent were histologically diagnosed as malignancies, according to research published online June 7 in the Journal of Cutaneous Pathology.

Tiffany Y. Chen, M.D., from Washington University School of Medicine in St. Louis, and colleagues retrospectively assessed dermatopathology samples from 2015 obtained from private and university locations. A total of 4,361 eligible cases of those with SK or irritated SK (ISK) and no other diagnosis in the clinical data were included in the study.

The researchers found that 86.2 percent of the cases identified as SK or ISK in the were actually SK or ISK; 10.7 percent were non-malignant diagnoses, including dermatofibroma. Overall, 3.1 percent of cases were histologically diagnosed as malignancies. Most of these (67 percent) were in situ or invasive , and 24.3 and 8.8 percent were and melanoma, respectively.

"Clinicians should be aware of this phenomenon. It is important to maintain a high index of suspicion when evaluating SK or ISK from the standpoint that it could possibly be malignant and consider a biopsy, especially if there are any changes over time," the authors write.

Explore further: Renal mass biopsy accurate for small renal masses

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Few want to receive skin cancer biopsy results face-to-face

February 15, 2016

(HealthDay)—For patients with suspected malignant melanoma or squamous cell carcinoma, most patients are happy to receive biopsy results by letter or telephone, according to a research letter published online Feb. 8 in ...

Superficial X-ray viable for basal, squamous cell carcinoma

August 6, 2012

(HealthDay) -- Superficial X-ray therapy remains a viable treatment for primary basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in select patients, according to a study published online July 23 in the Journal ...

Pain and itch may be signs of skin cancer

July 23, 2014

Asking patients if a suspicious skin lesion is painful or itchy may help doctors decide whether the spot is likely to be cancerous, according to a new study headed by Gil Yosipovitch, MD, Chairman of the Department of Dermatology ...

Commonly used painkillers may protect against skin cancer

May 29, 2012

A new study suggests that aspirin and other similar painkillers may help protect against skin cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings indicate that skin ...

Recommended for you

A new weapon for the war on cancer

June 28, 2017

Cancerous tumors are formidable enemies, recruiting blood vessels to aid their voracious growth, damaging nearby tissues, and deploying numerous strategies to evade the body's defense systems. But even more malicious are ...

The gene behind follicular lymphoma

June 28, 2017

Follicular lymphoma is an incurable cancer that affects over 200,000 people worldwide every year. A form of non-Hodgkin lymphoma, follicular lymphoma develops when the body starts making abnormal B-cells, which are white ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.