Exposure to cardiovascular risk factors linked with arterial distensibility in adolescence

Exposure to Cardiovascular Risk Factors Linked with Arterial Distensibility in Adolescence
Credit: University of Turku

The longitudinal study on children and adolescents conducted by the Research Centre of Applied and Preventive Cardiovascular Medicine at the University of Turku, Finland, is unique worldwide. The study shows that cardiovascular risk factors, such as overweight, high blood pressure, low-density lipoprotein (LDL) cholesterol and insulin resistance, are associated with arterial distensibility in adolescence.

Arterial distensibility decreases with age, i.e. arteries stiffen. Arterial stiffness is associated with the endpoints of cardiovascular diseases, such as stroke, heart attack and cardiac death.

Cardiovascular risk factors, such , affect in adulthood. The association of these risk factors with arterial elasticity from childhood to early adulthood has not been previously studied.

The study is part of the Special Turku Coronary Risk Factor Intervention Project (STRIP) of the Research Centre of Applied and Preventive Cardiovascular Medicine at the University of Turku. The study has followed initially over 1,000 children for 27 years. Their have been repeatedly measured from childhood to adulthood. The elasticity of the research subjects' arteries was measured with ultrasonography in the age of 11–19.

The study revealed that overweight, high blood pressure, LDL cholesterol and measured in childhood and adolescence are linked with arterial distensibility already at young age. Overweight, high blood pressure and LDL cholesterol can be influenced, for example, by promoting a healthy way of life, says Doctoral Candidate Hanna Mikola.

The results of the study can be utilised by concentrating the primordial prevention of cardiovascular diseases more actively on children and youth when trying to improve cardiovascular health throughout life.


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More information: Hanna Mikola et al. Cardiometabolic Determinants of Carotid and Aortic Distensibility From Childhood to Early Adulthood, Hypertension (2017). DOI: 10.1161/HYPERTENSIONAHA.117.09027
Journal information: Hypertension

Provided by University of Turku
Citation: Exposure to cardiovascular risk factors linked with arterial distensibility in adolescence (2017, June 30) retrieved 20 May 2019 from https://medicalxpress.com/news/2017-06-exposure-cardiovascular-factors-linked-arterial.html
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