Risk factors explain most heart failure risk in incident A-fib

June 19, 2017

(HealthDay)—Four modifiable factors account for most of the population attributable risk of heart failure among women with new-onset atrial fibrillation (AF), according to a study published online June 14 in JACC: Heart Failure.

Neal A. Chatterjee, M.D., from Brigham and Women's Hospital in Boston, and colleagues assessed 34,736 participants in the Women's Health Study free of prevalent cardiovascular disease at baseline to identify modifiable risk factors.

The researchers found that new-onset AF correlated with increased risk of in multivariable models (hazard ratio, 9.03). Once women with AF developed heart failure, there was an increase in all-cause and cardiovascular mortality (hazard ratios, 1.83 and 2.87). Systolic blood pressure >120 mm Hg, ≥30 kg/m², current tobacco use, and diabetes mellitus correlated with incident heart failure in models accounting for changes in risk factors after AF diagnosis. An estimated 62 percent of the population attributable risk of heart failure was explained by the combination of these four risk factors. Women who maintained or achieved optimal risk factor control had a progressive decreased risk of heart failure compared to women with three or four risk factors (hazard ratios for two, one, or no risk factors, 0.60, 0.40, and 0.14, respectively).

"In women with new-onset AF, modifiable , including obesity, hypertension, smoking, and diabetes, accounted for the majority of the population risk of heart failure," the authors write.

Explore further: Risk of heart failure up for rheumatoid arthritis patients

More information: Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Risk of heart failure up for rheumatoid arthritis patients

March 14, 2017
(HealthDay)—Patients with rheumatoid arthritis (RA) have increased risk of heart failure, according to a study published in the March 14 issue of the Journal of the American College of Cardiology.

Cardiorespiratory fitness impacts BMI-related heart failure risk

April 7, 2017
(HealthDay)—Higher body mass index (BMI) is associated with increased risk of heart failure, which is largely explained by differences in cardiorespiratory fitness (CRF), according to a study published online April 5 in ...

Preventing heart failure risk factors in midlife substantially lowers risk

November 28, 2016
Preventing the development of hypertension, obesity and diabetes by the age of 45 to 55 years may lead up to an 86 percent lower risk for heart failure through the remainder of life, according to research published today ...

Combined strategies better assess heart disease risks

June 2, 2017
A new strategy combining five separate medical tests provided a significantly better risk assessment of cardiovascular disease among adults, compared to traditional measures, according to a study published in Circulation.

Smoking may lead to heart failure by thickening the heart wall

September 13, 2016
Smoking is associated with thicker heart walls and reduction in the heart's pumping ability, two factors associated with increased risk of heart failure, according to new research in the American Heart Association's journal ...

Irregular heartbeat stronger risk factor for heart disease and death in women than in men

January 19, 2016
An irregular heartbeat (known as atrial fibrillation or AF) is a stronger risk factor for stroke, heart disease, heart failure and death in women than in men, although the cause is unclear, finds a study in The BMJ this week.

Recommended for you

Novel genetic study sheds new light on risk of heart attack

October 12, 2018
Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

Researchers say ritual for orthodox Jewish men may offer heart benefits

October 11, 2018
A pilot study led by researchers at the University of Cincinnati (UC) College of Medicine suggests Jewish men who practice wearing tefillin, which involves the tight wrapping of an arm with leather banding as part of daily ...

Markers of dairy fat consumption linked to lower risk of type two diabetes

October 10, 2018
Higher levels of biomarkers of dairy fat consumption are associated with a lower risk of developing type 2 diabetes, according to new research published today in PLOS Medicine. The study, in more than 60,000 adults, was undertaken ...

Seed oils are best for LDL cholesterol

October 9, 2018
If you want to lower your low-density lipoprotein cholesterol, called LDL or, colloquially, "bad cholesterol," the research is clear about one thing: You should exchange saturated fats with unsaturated fat. If you want to ...

Micropeptide restores heart function in mice

October 9, 2018
Researchers have discovered a micropeptide molecule that can restore normal heart function in mice, according to a study in eLife.

New risk test for sepsis for heart patients

October 5, 2018
Nearly one in four deaths in people with heart failure are caused by sepsis, according to new research.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.