Risk factors explain most heart failure risk in incident A-fib

June 19, 2017

(HealthDay)—Four modifiable factors account for most of the population attributable risk of heart failure among women with new-onset atrial fibrillation (AF), according to a study published online June 14 in JACC: Heart Failure.

Neal A. Chatterjee, M.D., from Brigham and Women's Hospital in Boston, and colleagues assessed 34,736 participants in the Women's Health Study free of prevalent cardiovascular disease at baseline to identify modifiable risk factors.

The researchers found that new-onset AF correlated with increased risk of in multivariable models (hazard ratio, 9.03). Once women with AF developed heart failure, there was an increase in all-cause and cardiovascular mortality (hazard ratios, 1.83 and 2.87). Systolic blood pressure >120 mm Hg, ≥30 kg/m², current tobacco use, and diabetes mellitus correlated with incident heart failure in models accounting for changes in risk factors after AF diagnosis. An estimated 62 percent of the population attributable risk of heart failure was explained by the combination of these four risk factors. Women who maintained or achieved optimal risk factor control had a progressive decreased risk of heart failure compared to women with three or four risk factors (hazard ratios for two, one, or no risk factors, 0.60, 0.40, and 0.14, respectively).

"In women with new-onset AF, modifiable , including obesity, hypertension, smoking, and diabetes, accounted for the majority of the population risk of heart failure," the authors write.

Explore further: Risk of heart failure up for rheumatoid arthritis patients

More information: Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Risk of heart failure up for rheumatoid arthritis patients

March 14, 2017
(HealthDay)—Patients with rheumatoid arthritis (RA) have increased risk of heart failure, according to a study published in the March 14 issue of the Journal of the American College of Cardiology.

Cardiorespiratory fitness impacts BMI-related heart failure risk

April 7, 2017
(HealthDay)—Higher body mass index (BMI) is associated with increased risk of heart failure, which is largely explained by differences in cardiorespiratory fitness (CRF), according to a study published online April 5 in ...

Preventing heart failure risk factors in midlife substantially lowers risk

November 28, 2016
Preventing the development of hypertension, obesity and diabetes by the age of 45 to 55 years may lead up to an 86 percent lower risk for heart failure through the remainder of life, according to research published today ...

Combined strategies better assess heart disease risks

June 2, 2017
A new strategy combining five separate medical tests provided a significantly better risk assessment of cardiovascular disease among adults, compared to traditional measures, according to a study published in Circulation.

Smoking may lead to heart failure by thickening the heart wall

September 13, 2016
Smoking is associated with thicker heart walls and reduction in the heart's pumping ability, two factors associated with increased risk of heart failure, according to new research in the American Heart Association's journal ...

Irregular heartbeat stronger risk factor for heart disease and death in women than in men

January 19, 2016
An irregular heartbeat (known as atrial fibrillation or AF) is a stronger risk factor for stroke, heart disease, heart failure and death in women than in men, although the cause is unclear, finds a study in The BMJ this week.

Recommended for you

Lasers used to detect risk of heart attack and stroke

August 18, 2017
Patients at risk of heart attacks and strokes may be spotted earlier thanks to a diagnosis tool that uses near-infrared light to identify high-risk arterial plaques, according to research carried out at WMG, University of ...

Cholesterol crystals are sure sign a heart attack may loom

August 17, 2017
A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state, during a heart attack.

How Gata4 helps mend a broken heart

August 15, 2017
During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead it replaces dead tissue with scars made of cells called fibroblasts ...

Injectable tissue patch could help repair damaged organs

August 14, 2017
A team of U of T Engineering researchers is mending broken hearts with an expanding tissue bandage a little smaller than a postage stamp.

'Fat but fit' are at increased risk of heart disease

August 14, 2017
Carrying extra weight could raise your risk of heart attack by more than a quarter, even if you are otherwise healthy.

Air pollution linked to cardiovascular disease; air purifiers may lessen impact

August 14, 2017
Exposure to high levels of air pollution increased stress hormone levels and negative metabolic changes in otherwise healthy, young adults in a recent study conducted in China. Air purifiers appeared to lessen the negative ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.