Idiopathic pulmonary fibrosis algorithm performs poorly

June 14, 2017

(HealthDay)—The traditional idiopathic pulmonary fibrosis (IPF) algorithm performs poorly, with positive predictive value of 42.2 percent and sensitivity of 55.6 percent, according to a study published in the June 1 issue of the Annals of the American Thoracic Society.

Brett Ley, M.D., from the University of California in San Francisco, and colleagues identified potential cases of IPF in the Kaiser Permanente Northern California adult population from 2000 to 2014 using the traditional IPF algorithm. A subset of 150 cases were validated by expert medical record and chest computed tomography review. To optimize , a modified IPF algorithm was derived and validated.

The researchers identified 2,608 cases among 5,389,627 at-risk adults using the traditional IPF algorithm. The annual incidence was 6.8/100,000 person-years, and was elevated for patients who were older, male, and white. For the IPF algorithm the positive predictive value was 42.2 percent, and the sensitivity was 55.6 percent. The estimated corrected incidence was 5.6/100,000 person-years. Compared with the traditional algorithm, the modified IPF algorithm improved positive predictive value but reduced sensitivity.

"A modification of the IPF algorithm may be useful for future population-based studies of IPF," the authors write.

Explore further: Culture-based screening algorithm cuts TB in immigrants

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Culture-based screening algorithm cuts TB in immigrants

March 17, 2015
(HealthDay)—Implementation of a culture-based screening algorithm in 2007 reduced the incidence of tuberculosis (TB) among immigrants and refugees bound for the United States, according to a study published in the March ...

EHR algorithm can be used to detect, classify diabetes

December 10, 2012
(HealthDay)—Data from electronic health records (EHRs) can be used to detect more cases of diabetes than claim codes alone and can be used to accurately distinguish between type 1 and type 2 diabetes, according to a study ...

Machine learning may help in early identification of severe sepsis

May 24, 2017
A machine-learning algorithm has the capability to identify hospitalized patients at risk for severe sepsis and septic shock using data from electronic health records (EHRs), according to a study presented at the 2017 American ...

Data-driven algorithm yields notable improvements in HbA1c

December 14, 2016
(HealthDay)—A data-driven algorithm for personalized diabetes care can yield substantial improvements in hemoglobin A1c (HbA1c), according to a study published online Dec. 5 in Diabetes Care.

Advances in predictive hypoglycemia-minimizing technology from Animas-JDRF collaboration

June 16, 2014
Animas Corporation today shared encouraging results from its predictive hypoglycemia-minimizing algorithm in development. Data from a clinical feasibility study demonstrated that the algorithm was capable of helping maintain ...

Biopsy-based algorithm found accurate for small renal masses

February 9, 2013
(HealthDay)—Compared with final pathology, biopsy of small renal masses (SRMs) can be accurately used in a treatment algorithm to direct management, according to research published in the February issue of The Journal of ...

Recommended for you

New molecule may hold the key to triggering the regeneration and repair of damaged heart cells

August 21, 2017
New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases. For the first time, researchers have identified ...

Researchers investigate the potential of spider silk protein for engineering artificial heart

August 18, 2017
Ever more people are suffering from cardiac insufficiency, despite significant advances in preventing and minimising damage to the heart. The main cause of reduced cardiac functionality lies in the irreversible loss of cardiac ...

Lasers used to detect risk of heart attack and stroke

August 18, 2017
Patients at risk of heart attacks and strokes may be spotted earlier thanks to a diagnosis tool that uses near-infrared light to identify high-risk arterial plaques, according to research carried out at WMG, University of ...

Cholesterol crystals are sure sign a heart attack may loom

August 17, 2017
A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state, during a heart attack.

How Gata4 helps mend a broken heart

August 15, 2017
During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead it replaces dead tissue with scars made of cells called fibroblasts ...

Injectable tissue patch could help repair damaged organs

August 14, 2017
A team of U of T Engineering researchers is mending broken hearts with an expanding tissue bandage a little smaller than a postage stamp.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.