Olive oil, ibuprofen may have synergistic effects

June 14, 2017

(HealthDay)—The combination of extra virgin olive oil (EVOO) and ibuprofen at a therapeutic dose is superior to the two compounds used separately, according to an experimental study published online June 7 in the International Journal of Rheumatic Diseases.

Walla'a A. Osman, from Cairo University, and colleagues examined the analgesic, anti-pyretic, and anti-inflammatory activities of EVOO at a dose of 8 mL/kg body weight compared with ibuprofen as an individual drug therapy and in combination with two different doses of ibuprofen (therapeutic dose, 100 mg/kg; low dose, 40 kg/mg). One hundred thirty-two adult healthy male Swiss albino mice were examined. The anti-pyretic effect was assessed using brewer's yeast-induced pyrexia, and two different models were used to examine anti-inflammatory activity.

The researchers found that in all the treated groups there was significant protection. Compared with the two compounds used separately, the combination of EVOO and ibuprofen at its therapeutic dose showed superiority.

"Using EVOO with the therapeutic dose of ibuprofen showed in controlling the cardinal signs of acute inflammation rather than using alone," the authors write.

Explore further: A taste for olive oil could provide insight into its anti-inflammatory properties

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

A taste for olive oil could provide insight into its anti-inflammatory properties

October 8, 2012
(Medical Xpress)—Deakin University researchers are investigating the anti-inflammatory properties of virgin olive oil to see if it as the potential to protect against the inflammation involved in muscle wasting conditions ...

A study demonstrates that ibuprofen improves bone repair after surgery or a fracture

July 3, 2012
A study conducted at the University of Granada hasdemonstrated that ibuprofen ­–a non-steroidal anti-inflammatory drug (NSAID)­– has beneficial effects on bone repair after afracture or following bone ...

European watchdog seeks tighter guidelines on ibuprofen

April 13, 2015
A European panel on Monday backed tougher guidelines on ibuprofen after research found high doses of the popular painkiller were linked to a small increase in cardiac and stroke risk.

Some benefit for curcuminoids in knee osteoarthritis

May 26, 2017
(HealthDay)—Curcuminoids seem beneficial for knee osteoarthritis (OA), although they are less effective for pain relief than ibuprofen, according to a review and meta-analysis published online May 4 in the International ...

Recommended for you

New molecule may hold the key to triggering the regeneration and repair of damaged heart cells

August 21, 2017
New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases. For the first time, researchers have identified ...

Researchers investigate the potential of spider silk protein for engineering artificial heart

August 18, 2017
Ever more people are suffering from cardiac insufficiency, despite significant advances in preventing and minimising damage to the heart. The main cause of reduced cardiac functionality lies in the irreversible loss of cardiac ...

Lasers used to detect risk of heart attack and stroke

August 18, 2017
Patients at risk of heart attacks and strokes may be spotted earlier thanks to a diagnosis tool that uses near-infrared light to identify high-risk arterial plaques, according to research carried out at WMG, University of ...

Cholesterol crystals are sure sign a heart attack may loom

August 17, 2017
A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state, during a heart attack.

How Gata4 helps mend a broken heart

August 15, 2017
During a heart attack, blood stops flowing into the heart; starved for oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead it replaces dead tissue with scars made of cells called fibroblasts ...

Injectable tissue patch could help repair damaged organs

August 14, 2017
A team of U of T Engineering researchers is mending broken hearts with an expanding tissue bandage a little smaller than a postage stamp.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.