FDA warns on mixing opioid addiction treatments, other meds

September 20, 2017 by Linda A. Johnson

The Food and Drug Administration has issued new warnings about the dangers of combining medication for opioid addiction with antidepressants and other drugs that also slow breathing and brain activity.

The FDA warns that mixing such drugs can cause difficulty breathing, coma or death and should be done with caution.

Many patients fighting opioid addiction by taking methadone or buprenorphine (byoo-preh-NOR'-feen) also take other that slow action of the central nervous system. Those include the medications Ambien and Lunesta for insomnia, Valium and Xanax for anxiety, muscle relaxers Soma and Zanaflex and Abilify, Invega, Saphris and others.

Meanwhile, the agency stressed that treating opioid addiction with medication is crucial to curbing the U.S. opioid epidemic.

Explore further: Starting opioid addiction treatment in the ED is cost-effective

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