Reports reveal racial and ethnic disparities in lupus rates

September 11, 2017

Two new papers reveal striking racial and ethnic disparities in the incidence and prevalence of lupus, a systemic autoimmune disease that can affect virtually any organ system. The reports, which are published in Arthritis & Rheumatology, provide the latest information from lupus registries in California and New York.

In the reports from the California Lupus Surveillance Project and the Manhattan Lupus Surveillance Program, investigators estimated the frequency of lupus in a combined 2.4 million residents living in San Francisco and Manhattan. They found a similar overall age-adjusted annual incidence of lupus of 4.6 per 100,000. The age-adjusted prevalence was slightly greater in California than Manhattan (84.8 versus 62.2 per 100,000).

Women experienced higher rates of lupus than men, and the prevalence of lupus in both Hispanics and Asians was greater than that seen in Whites, but not as frequent as Blacks. The age-standardized prevalences in per 100,000 for the California and Manhattan registries, respectively, were 458.1 and 210.9 for Black women, 177.9 and 138.3 for Hispanic women, 149.7 and 91.2 for Asian women, and 109.8 and 64.3 for White women.

"There is a paucity of population-based studies of incidence and prevalence of lupus among Asians and Hispanics in the United States," said University of California, San Francisco's Maria Dall'Era, MD, lead author of the California report. "These registries were able to address this deficiency and provide contemporary epidemiological estimates."

The findings indicate that doctors should be vigilant in looking for lupus in not only Black patients, but also in Asians and Hispanics. "Physicians should consider the diagnosis especially when patients come in with symptoms that could be consistent with lupus such as arthritis, rashes, and signs of kidney disease," said NYU School of Medicine's Peter Izmirly, MD, lead author of the Manhattan report. "Hopefully this can lead to earlier diagnosis of the disease and better care."

Additional studies are needed to determine the contributions of genetic and biological factors in addition to social and environmental factors that might play a role in racial and ethnic variation in the risk of lupus. "With this information, we will better understand how to diagnose and treat in affected populations with the ultimate goal of disease prevention," said Dr. Dall'Era.

Explore further: New study reveals hidden burden of Lupus among Hispanic and Asian women in Manhattan

More information: Maria Dall'Era et al, The Incidence and Prevalence of Systemic Lupus Erythematosus in San Francisco County, California: The California Lupus Surveillance Project, Arthritis & Rheumatology (2017). DOI: 10.1002/art.40191

Related Stories

New study reveals hidden burden of Lupus among Hispanic and Asian women in Manhattan

September 11, 2017
Within Manhattan's diverse population, the chronic and often debilitating autoimmune disease lupus affects Hispanic and Asian women more frequently than white women, according to a new study led by investigators at NYU School ...

Lower mortality rates among Asian and Hispanic lupus patients

January 15, 2015
A new study by researchers from Brigham and Women's Hospital in Boston, Massachusetts reveals that Asian and Hispanic patients with systemic lupus erythematosus (SLE) have lower mortality rates compared to Black, White, or ...

Race, ethnicity and education levels linked to delays accessing lupus specialty care

November 13, 2016
Lupus patients who are African-American or Asian, or those who have attained only a high school education or less, had longer delays in seeing a rheumatologist or nephrologist for a confirmed diagnosis than other groups, ...

Lupus may contribute to pregnancy-related complications

February 1, 2016
A new study found that lupus during pregnancy may have negative health impacts for women and their babies. The study included 13,598 Swedish women in their first pregnancy, and all were singleton pregnancies. Preeclampsia, ...

New blood test detects stroke and heart attack risk in lupus patients with no CVD symptoms

June 15, 2017
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference have shown that a specific biomarker detected in the blood of lupus patients with no symptoms of cardiovascular ...

Large multi-ethnic study identifies many new genetic markers for lupus

July 17, 2017
Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

Recommended for you

Old World monkeys could be key to a new, powerful rheumatoid arthritis therapy

November 16, 2017
In the quest for a new and more effective treatment for rheumatoid arthritis, researchers from the Keck School of Medicine of USC looked to a primate that mostly roams the land in Asia, the Middle East and Africa. It was ...

Study lists foods for fighting rheumatoid arthritis symptoms and progression

November 8, 2017
A list of food items with proven beneficial effects on the progression and symptoms of rheumatoid arthritis is provided in a new study published today in Frontiers in Nutrition. The authors suggest incorporating these foods ...

Prototype equipment can detect rheumatoid arthritis

September 28, 2017
According to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners have designed a device that shows the difference between healthy fingers and arthritic ...

Improving the recognition of anxiety and depression in rheumatoid arthritis

August 28, 2017
A study conducted by Keele University shows that patients with rheumatoid arthritis who are also suffering with anxiety or depression may avoid talking to their GP about their mental health symptoms.

How you think about your arthritis makes a difference

August 24, 2017
(HealthDay)—How well you cope with knee arthritis depends a lot on your mental outlook, a new study suggests.

Treating arthritis with algae

August 23, 2017
Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae. ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.