Study cites race and socioeconomic factors as influential in NSCLC patient survival rates

October 16, 2017, International Association for the Study of Lung Cancer

New research found race and specific socioeconomic factors to have a significant influence on disparities in the survival rates of non-small cell lung cancer (NSCLC) patients. Dr. Yanyan Lou of the Mayo Clinic in the United States presented these findings today at the International Association for the Study of Lung Cancer (IASLC) 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan.

While NSCLC patient outcomes have improved over time, the influence of race and socioeconomic factors on these outcomes has historically not been well studied. By using data from the National Cancer Database on NSCLC incident cases from 2004-2013 in the U.S., Dr. Lou and her team sought to determine whether a correlation exists between patients' overall survival (OS) and various socioeconomic factors and race.

Of the more than 1.1 million cases studied, 86.4 percent were White, 10.6 percent were Black, and smaller proportions were Asian and Hispanic. Income was fairly evenly distributed. Additionally, a majority of the cases were individuals who were insured, lived in a metro area and received care at non-academic facilities.

The researchers found that the median overall survival was significantly better for Asians and Hispanics as compared to Whites and Blacks. The range of medians between the highest (Asians) and lowest (Blacks) OS rates was over half a year (6.7 months). Additionally, they found that outcomes were worse when there was a higher rate of comorbidity with other diseases, advanced stage and treatment at a community or low-volume center. Finally, the researchers determined that specific socioeconomic factors were associated with worse outcomes, including lower education levels, lower median income and uninsured status.

Based on this study, the researchers determined that the influence of race and specific socioeconomic factors is significant. In order to ensure fair treatment and patient outcomes, these factors must be considered in the provision of care for NSCLC.

"The study is the largest analysis on the correlation between and and NSCLC outcomes to date," said Dr. Lou. "Our findings indicate that improving outcomes for NSCLC doesn't solely rely on advancements in medicine, but also on ensuring more equitable health care delivery."

Explore further: Racial disparities persist in treatment and survival of early stage lung cancer

Related Stories

Racial disparities persist in treatment and survival of early stage lung cancer

March 16, 2017
Analysis of the largest American cancer database indicates that racial disparities persist in the treatment and outcomes of patients diagnosed with stage I non-small cell lung cancer (NSCLC). Despite increased availability ...

Advanced stage NSCLC patients receiving treatment have better OS than untreated patients

January 18, 2017
Non-small cell lung cancer (NSCLC) patients with advanced disease receiving standard of care treatment have a higher overall survival (OS) than similar patients not receiving treatment.

Foreign-born hispanics have survival advantage in NSCLC

August 22, 2013
(HealthDay)—Compared with non-Hispanic whites (NHWs) and U.S.-born Hispanics, foreign-born Hispanics with non-small-cell lung cancer (NSCLC) have a reduced risk of disease-specific mortality, according to research published ...

Socioeconomic factors—not race or ethnicity—influence survival of younger patients with multiple myeloma

August 22, 2016
Advances in the treatment of multiple myeloma, a cancer that forms in a type of white blood cell, have led to improved survival predominantly among young and white patients, with less of an increase in survival observed in ...

Hispanic lung cancer patients have higher survival than non-Hispanic white patients

September 6, 2012
Analysis of non-small cell lung cancer (NSCLC) patient records in the California Cancer Registry (CCR) database during the 20-year period of 1988-2008 indicates that Hispanics/Latinos with NSCLC have a higher overall survival ...

Receiving curative lung cancer surgery varies by state

November 13, 2015
The likelihood of receiving curative-intent surgery for patients with early-stage non-small cell lung cancer (NSCLC) varies substantially from state to state, according to data presented at the Eighth American Association ...

Recommended for you

Two ways cancer resists treatment are actually connected, with one activating the other

December 18, 2018
Drugs that target BRAF and MEK in cancer have shown promise in treating a subset of melanoma that carries a mutation in the BRAF gene, but drug resistance usually emerges, reversing the benefit of these drugs and limiting ...

HPV discovery raises hope for new cervical cancer treatments

December 18, 2018
Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus (HPV) that could lead to new treatments for cervical cancer and other cancers caused by the virus.

Vaccine, checkpoint drugs combination shows promise for pancreatic cancers

December 18, 2018
Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people ...

Researchers identify ways breast cancer avoids immune system detection

December 18, 2018
Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this new therapy, and an interdisciplinary team ...

Metal chemotherapy drugs boost the impact of immunotherapy in cancer

December 18, 2018
Due to their powerful tumour-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) ...

10-year follow-up after negative colonoscopies linked to lower colorectal cancer risk

December 17, 2018
Ten years after a negative colonoscopy, Kaiser Permanente members had 46 percent lower risk of being diagnosed with and were 88 percent less likely to die from colorectal cancer compared with those who did not undergo colorectal ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.