Lower microbial diversity in the gut in anorexia nervosa

December 4, 2017

(HealthDay)—Females with anorexia nervosa (AN) have lower gut microbial diversity, according to a study published online Nov. 13 in the International Journal of Eating Disorders.

Sabrina Mörkl, M.D., from the University of Graz in Austria, and colleagues included 106 female patients in a cross-sectional study: 18 with AN, 20 athletes, 26 normal-weight, 22 overweight, and 20 . DNA was extracted from stool samples and 16S rRNA gene analysis was performed.

The researchers found that patients with AN and obese participants had lower alpha compared with other groups, while the highest alpha diversity was seen for athletes. Significant associations were identified for several categories with community structure: body fat parameters, serum lipids, C-reactive protein, depression scales, and smoking. In comparative analysis, Coriobacteriaceae was the only enriched phylotype in AN versus other entities.

"This study provides further evidence of intestinal dysbiosis in AN and sheds light on characteristics of the in different body mass index and physical activity groups," the authors write. "These insights point to new modulation possibilities of the which could improve the standard therapy of AN."

Explore further: ACG: fecal transplant safe in primary sclerosing cholangitis

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

ACG: fecal transplant safe in primary sclerosing cholangitis

October 16, 2017
(HealthDay)—Fecal microbiota transplantation (FMT) from a rationally selected donor seems safe and effective for patients with primary sclerosing cholangitis (PSC), according to a study presented at the World Congress of ...

Both obese and anorexic women have low levels of 'feel good' neurosteroid

November 10, 2017
Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.

Gut microbiome diversity lower in chronic pelvic pain syndrome

July 25, 2016
(HealthDay)—Gut microbiome diversity is significantly lower in patients with chronic pelvic pain syndrome, with wider clustering, according to a study published in the August issue of The Journal of Urology.

Probiotics linked to weight loss in obese, overweight

October 29, 2017
(HealthDay)—Short-term probiotics are associated with reductions in body weight, body mass index (BMI), and fat percentage in overweight or obese subjects, according to research published online Oct. 18 in Obesity Reviews.

Microbiome linked to infectious complications in AML

May 9, 2016
(HealthDay)—For patients with acute myelogenous leukemia (AML) undergoing induction chemotherapy (IC), gastrointestinal microbiome composition is associated with infectious complications, according to a study published ...

Researchers study mediating role of leptin in bulimia

October 26, 2017
(HealthDay)—Leptin appears to mediate the correlation between weight suppression (WS) and duration of illness in bulimia nervosa-syndrome (BN-S), according to a study published online Oct. 16 in the International Journal ...

Recommended for you

Evening hours may pose higher risk for overeating, especially when under stress, study finds

January 16, 2018
Experiments with a small group of overweight men and women have added to evidence that "hunger hormone" levels rise and "satiety (or fullness) hormone" levels decrease in the evening. The findings also suggest that stress ...

Bariatric surgery prolongs lifespan in obese

January 16, 2018
Obese, middle-age men and women who had bariatric surgery have half the death rate of those who had traditional medical treatment over a 10-year period, reports a study that answers questions about the long-term risk of the ...

Sugar-sweetened drinks linked to overweight and obesity in children, adults: Analysis of new studies

December 23, 2017
A new review of the latest evidence on sugar-sweetened beverages (SSBs)- which includes 30 new studies published between 2013 and 2015 (and none of them industry sponsored) - concludes that SSB consumption is associated with ...

As income rises, women get slimmer—but not men

December 21, 2017
(HealthDay)—A comprehensive survey on the widening American waistline finds that as paychecks get bigger, women's average weight tends to drop.

Policy and early intervention can curb obesity rates

December 18, 2017
More information and emphasis on dietary lifestyle changes that prevent obesity, and its comorbidities, have not reduced the rise in obesity in U.S. adults and adolescents, according to a recent study in the New England Journal ...

Warning labels can help reduce soda consumption and obesity, new study suggests

December 15, 2017
Labels that warn people about the risks of drinking soda and other sugar-sweetened beverages can lower obesity and overweight prevalence, suggests a new Johns Hopkins Bloomberg School of Public Health study.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.