Rheumatic diseases associated with increased dementia risk

December 20, 2017

(HealthDay)—Patients with various rheumatic diseases have an increased risk of dementia, according to a study published online Dec. 15 in the International Journal of Rheumatic Diseases.

Kuan-Ting Chen, from Chung Shan Medical University in Taichung, Taiwan, and colleagues extracted data from the Taiwan National Health Insurance Research Database to examine the correlation between and dementia. A total of 10,180 cases with dementia and 61,080 controls were recruited during 2000 to 2010 and matched by age, gender, and index date.

The researchers found that among females, there was a significantly higher risk of dementia in Sjögren's syndrome (SS), (SLE), and osteoarthritis (OA); for males, there was a significantly higher risk of dementia in SS, (PsA), and OA. A significant difference was demonstrated in SLE and OA among the younger group (aged 40 to 64 years) and in SS and OA among the older group (aged ≥65 years).

"In this population-based case-control study, we found that patients with rheumatoid arthritis, SS, SLE, PsA, and OA are significantly associated with a higher risk of than those without rheumatic diseases," the authors write. "We hypothesized that inflammation and medications are two possible mechanisms."

Explore further: Lupus linked with increased risk of dementia

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Lupus linked with increased risk of dementia

November 8, 2017
A new International Journal of Geriatric Psychiatry study indicates that the risk of dementia may be elevated in individuals with systemic lupus erythematosus (SLE), an autoimmune disease affecting a range of systems including ...

Colonic diverticular disease may increase dementia risk

December 6, 2016
(HealthDay)—Patients with colonic diverticular disease may be at an increased risk for dementia, according to a study published Nov. 23 in the Journal of Gastroenterology and Hepatology.

Colonic diverticular disease linked to dementia risk

April 11, 2016
(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in the Journal of Gastroenterology and Hepatology.

Proton pump inhibitor use ups pneumonia risk in dementia

March 30, 2017
(HealthDay)—For patients with dementia, proton pump inhibitor (PPI) use is associated with increased risk of pneumonia, according to a study published online March 21 in the Journal of the American Geriatrics Society.

Previous bacterial infection increases risk of newly-diagnosed Sjogren's syndrome syndrome

June 15, 2017
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR) 2017 have shown a link between newly-diagnosed Sjögren's syndrome (SjS) and previous infection with nontuberculous mycobacteria ...

Autoimmune disease may be linked to heightened dementia risk

March 1, 2017
Autoimmune disease may be linked to a heightened risk of dementia, indicates a large long term study, published in the Journal of Epidemiology & Community Health.

Recommended for you

Pregnancy history may be tied to Alzheimer's disease

July 18, 2018
A woman's history of pregnancy may affect her risk of Alzheimer's disease decades later, according to a study published in the July 18, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. ...

Molecular tracer, seen with PET scan, shows concentrations of abnormal proteins

July 17, 2018
In a small study of military personnel who had suffered head trauma and had reported memory and mood problems, UCLA researchers found brain changes similar to those seen in retired football players with suspected chronic ...

Yale-developed test for Alzheimer's disease directly measures synaptic loss

July 16, 2018
Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer's disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, ...

New study highlights Alzheimer's herpes link, experts say

July 12, 2018
A new commentary by scientists at the Universities of Manchester and Edinburgh on a study by Taiwanese epidemiologists supports the viability of a potential way to reduce the risk of Alzheimer's disease.

Practice imperfect—repeated cognitive testing can obscure early signs of dementia

July 12, 2018
Alzheimer's disease (AD) is a progressive, neurodegenerative condition that often begins with mild cognitive impairment or MCI, making early and repeated assessments of cognitive change crucial to diagnosis and treatment.

The 'Big Bang' of Alzheimer's: Scientists ID genesis of disease, focus efforts on shape-shifting tau

July 10, 2018
Scientists have discovered a "Big Bang" of Alzheimer's disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.