Follow-up delta CHA2DS2-VASc score better predicts CVA in A-fib

Follow-up delta CHA<sub>2</sub>DS<sub>2</sub>-VASc score better predicts

(HealthDay)—Assessing change in the CHA2DS2-VASc score over time is more predictive of ischemic stroke in patients with atrial fibrillation (AF) than the baseline score, according to a study published in the Jan. 16 issue of the Journal of the American College of Cardiology.

Tze-Fan Chao, M.D., from the Taipei Veterans General Hospital in Taiwan, and colleagues compared the effectiveness of assessing ischemic stroke risk in 31,039 patients with AF using the CHA2DS2-VASc , based on the baseline risk factors, and the Delta CHA2DS2-VASc score, which reflects the change in score between baseline and follow-up.

The researchers found that the CHA2DS2-VASc score remained unchanged in only 40.8 percent of patients. The majority of the 4,103 patients who experienced ischemic stroke had a Delta CHA2DS2-VASc score ≥1 (89.4 percent, versus 54.6 percent in patients without ischemic stroke). Nearly two-thirds of who had an ischemic stroke (64.4 percent) had at least one new-onset comorbidity, most commonly hypertension. The Delta CHA2DS2-VASc score significantly better predicted ischemic stroke compared to baseline or follow-up CHA2DS2-VASc scores, based on the C-index and the net reclassification index.

"The Delta CHA2DS2-VASc score, reflecting the change in score between baseline and follow-up, was strongly predictive of , reflecting how stroke risk in AF is a dynamic process due to increasing age and incident comorbidities," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.


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Citation: Follow-up delta CHA2DS2-VASc score better predicts CVA in A-fib (2018, January 9) retrieved 14 December 2019 from https://medicalxpress.com/news/2018-01-follow-up-delta-cha2ds2-vasc-score-cva.html
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