Screening mammography for women 40-49 detects more cancers compared with older age groups

March 13, 2018, American Roentgen Ray Society

When compared to the screening population ages 50 and over, screening mammography in women ages 40-49 detects 19.3% additional cancers at the expense of an overall 1.5% increase in callbacks and 0.1% in increased biopsies, according to a study to be presented at the ARRS 2018 Annual Meeting, set for April 22-27 in Washington, DC.

The study to be presented by Abid Irshad of the Medical University of South Carolina examined the effectiveness of screening mammography between ages 40-49 in comparison to age groups 50-59 and 60-69. More than 41,000 screening mammography exams were examined for callbacks and recall rate, biopsies performed, cancers detected, and sensitivity and specificity of screening mammography.

Overall, 41,028 were performed with 5,196 callbacks (12.7% recall rate), 1,164 biopsies, and 326 cancers detected. Women ages 40-49 had 8,913 mammograms, 1,518 callbacks (17% recall rate), 306 biopsies, and 52 cancers detected. Women ages 50-59 had 13,288 mammograms, 1,659 callbacks (12.5% recall rate), 371 biopsies, and 103 cancers detected, while women ages 60-69 had 12,119 mammograms, 1,239 callbacks (10.2% recall rate), 302 biopsies and 89 cancers detected. Overall, the women ages 50 and over had a total of 31,385 mammograms, 3,504 callbacks (11.2% recall rate), 836 biopsies, and 270 cancers detected. By adding the women ages 40-49 to the screening population of 50 and over, the overall callback rate increased 1.5%, the rate increased 0.1% and 19.3% more cancers were detected.

The study results showed that there was a higher number of callbacks among women ages 40-49 compared to women ages 50-59 (17% compared with 12.5%) and to women ages 60-69 (17% compared with 10.2%). There was also a lower positive biopsy rate among women ages 40-49 compared with women over 50. The number of cancers detected in ages 40-49 was not significantly different from 50-59 or 60-69.

Explore further: Comparison of screening recommendations indicates annual mammography

Related Stories

Comparison of screening recommendations indicates annual mammography

August 21, 2017
When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates. A new study compares the number of deaths that might be prevented as a result ...

Screening has had 'little impact' on falling breast cancer deaths in the Netherlands

December 5, 2017
Breast screening in the Netherlands seems to have had a marginal effect on breast cancer mortality over the past 24 years, suggests research in The BMJ today.

Mammo outcomes improve when docs compare prior screenings

November 3, 2016
The recall rate of screening mammography is reduced when radiologists compare with more than one prior mammogram, a study published in the October 2016 issue of the American Journal of Roentgenology said.

Does MRI plus mammography improve detection of new breast cancer after breast conservation therapy?

June 22, 2017
A new article published by JAMA Oncology compares outcomes for combined mammography and MRI or ultrasonography screenings for new breast cancers in women who have previously undergone breast conservation surgery and radiotherapy ...

Women prefer getting mammograms every year

November 21, 2017
Women prefer to get their mammograms every year, instead of every two years, according to a new study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

Recommended for you

Targeting the engine room of the cancer cell

June 18, 2018
Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug ...

Study suggests well-known growth suppressor actually fuels lethal brain cancers

June 18, 2018
Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it ...

Researchers create novel combination as potential therapy for high-risk neuroblastoma

June 18, 2018
Researchers at VCU Massey Cancer Center in Richmond, Virginia, have identified a promising target to reverse the development of high-risk neuroblastoma and potentially inform the creation of novel combination therapies for ...

Genomics offers new treatment options for infants with range of soft tissue tumors

June 18, 2018
The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed ...

Standard myelofibrosis drug can awaken 'dormant' lymphoma

June 18, 2018
Most patients with myelofibrosis, a rare chronic disorder of the haematopoietic cells of the bone marrow, benefit from drugs from the JAK2 inhibitor class: symptoms are relieved, survival extended and general quality-of-life ...

Breast cancer researcher warns against online genetic tests

June 18, 2018
We have never been so fascinated by the secrets inside our cells.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.