Severe eczema may be linked to heart disease risk

May 24, 2018

(HealthDay)—Sufferers of severe eczema may be at greater risk for heart attack, stroke and irregular heartbeat, British researchers report.

Although the added risk is small, it's important from a public health perspective because eczema affects up to 10 percent of adults, the researchers said.

Eczema is a term for several types of skin swelling marked by dry, itchy skin and rashes.

Because this was an observational study, the researchers couldn't prove eczema caused the increased . But they said that, given the large number of people included in the study, the association appears strong.

Dr. Sinead Langan, of the London School of Hygiene and Tropical Medicine, led the international research team.

To quantify the risk, the researchers analyzed data for more than 385,000 adults (average age 43) with eczema. Each was matched with up to five people of similar age and gender who didn't have eczema.

Patients were classified as having mild, moderate or severe eczema and were followed for an average of five years.

Those with severe eczema had a 20 percent increased risk of stroke and a 40 percent to 50 percent greater risk of unstable angina, , atrial fibrillation and death from heart . This group also had a 70 percent increased risk for heart failure, the study authors said.

These risks remained after the researchers accounted for such factors as weight, smoking and alcohol use.

Their findings were published May 23 in the journal BMJ.

"Severe and predominantly active are associated with an increased risk of cardiovascular outcomes. Targeting cardiovascular prevention strategies among these patients should be considered," the researchers said in a journal news release.

In an accompanying editorial, Dr. John Ingram, a consultant dermatologist at Cardiff University in Wales, said these results helped clarify the conflicting evidence about eczema and heart disease risk.

The findings may also shed light on the value of using costly new biologic drugs to control severe . Exploring whether these drugs can reduce disease risks is the next step, Ingram said.

Explore further: Eczema's effects more than skin deep

More information: To learn more about eczema, visit the American Academy of Dermatology.

Related Stories

Eczema's effects more than skin deep

July 29, 2016
(HealthDay)—People dealing with the itchy skin condition known as eczema may have other medical conditions to cope with as well, including heart disease, a dermatologist says.

Study finds eczema, short stature not associated overall

December 10, 2014
Eczema, an itchy chronic inflammatory disease of the skin, was not associated overall with short stature in an analysis of data from several studies, although a small group of children and adolescents with severe eczema who ...

Eczema can take a toll on adults

July 27, 2017
(HealthDay)—The itchy, rashy skin condition eczema sometimes takes a heavier toll on adults than children, an expert says.

High prevalence of alcohol use disorders in eczema

April 4, 2017
(HealthDay)—Patients with eczema have a high prevalence of alcohol use disorders, according to a study published online March 27 in the British Journal of Dermatology.

Sun effects on skin reveal eczema therapy clues

June 19, 2017
Exposure to sunlight releases a compound from the skin that can alleviate symptoms of eczema, research has found.

AD most commonly used term in literature for atopic dermatitis

July 15, 2016
(HealthDay)—Atopic dermatitis (AD) is most commonly referred to as AD in the literature, according to a review published online July 8 in Allergy.

Recommended for you

A bad influence—the interplay between tumor cells and immune cells

October 16, 2018
Research at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) yielded new insights into the environment surrounding different types of lung tumors, and described how these complex cell ecosystems may in turn ...

Function of neutrophils during tumor progression unraveled

October 15, 2018
Researchers at The Wistar Institute have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and ...

Immune health maintained by meticulously ordered DNA

October 15, 2018
Walter and Eliza Hall Institute researchers have revealed how immune health is maintained by the exquisite organisation skills of a protein called Pax5.

New immunotherapy targeting blood-clotting protein

October 15, 2018
Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier—which keeps large molecules in the blood from entering the brain—becomes abnormally permeable, ...

Enzyme that triggers autoimmune responses from T-cells in patients with MS found

October 11, 2018
A team of researchers from Switzerland, the U.S. and Spain has isolated an enzyme that triggers an autoimmune response from T-cells in patients with MS. In their paper published in the journal Science Translational Medicine, ...

Scientists reveal new cystic fibrosis treatments work best in inflamed airways

October 11, 2018
A new UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient's airway is inflamed. This is the first study to evaluate ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.