No new adverse events reported for DTaP vaccination

June 4, 2018

(HealthDay)—No new or unexpected safety issues have been identified in association with diphtheria-tetanus-acellular pertussis (DTaP) vaccines in the United States, according to a study published online June 4 in Pediatrics.

Pedro L. Moro, M.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues searched the Vaccine Adverse Event Reporting System (VAERS) for U.S. reports of DTaP vaccinations from Jan. 1, 1991, through Dec. 31, 2016. Medical records were reviewed for death reports, and a random sample of non-fatal serious reports.

The researchers found that 50,157 reports were received by VAERS after DTaP vaccination; 87.7 percent reported concomitant administration of other vaccines and 11.2 percent of reports were serious. Vaccination occurred at a median age of 19 months. Injection site erythema, pyrexia, site swelling, erythema, and injection site warmth were the most frequently reported events (25.3, 19.8, 15.0, 11.2, and 9.6 percent, respectively). Using Empirical Bayesian data mining, elevated values for vaccination errors were identified for three of the DTaP vaccines.

"The observed disproportionate reporting for some non-serious vaccination errors calls for better education of providers on the specific indications for each of the DTaP vaccines," the authors write.

Explore further: Efficacy of DTaP, tdap holds despite pertactin deficiency

More information: Abstract/Full Text
Editorial

Related Stories

Efficacy of DTaP, tdap holds despite pertactin deficiency

April 12, 2016
(HealthDay)—Despite an increased proportion of Bordetella pertussis isolates lacking pertactin, vaccine effectiveness (VE) is still high in Vermont for the five-dose diphtheria, tetanus, and acellular pertussis vaccine ...

Timing of DTaP vaccine not tied to food allergies at age one year

December 30, 2015
(HealthDay)—Timing of the diphtheria-tetanus-acellular pertussis (DTaP) vaccination is not tied to child food allergies; however, children with delayed DTaP have less eczema, according to a study published online Dec. 28 ...

Protection against whooping cough waned during the five years after fifth dose of DTaP

September 12, 2012
OAKLAND, Calif. − Protection against whooping cough (also called pertussis) waned during the five years after the fifth dose of the combined diphtheria, tetanus, acellular pertussis (DTaP) vaccine, according to researchers ...

Maternal pertussis vaccination reduces risk for newborns by more than 90 percent

April 3, 2017
Among infants of women who received the Tdap pertussis booster vaccine during pregnancy, the risk of contracting pertussis was reduced by an estimated 91 percent during the first two months of life ? the critical period before ...

Researcher says whooping cough vaccines effective, despite outbreaks

November 29, 2012
(Medical Xpress)—Despite recent outbreaks of pertussis (whooping cough)—a highly contagious bacterial disease that is preventable by the current pertussis vaccines—Yale researcher Dr. Eugene Shapiro maintains in an ...

Protecting newborns from pertussis

August 24, 2017
Dear Mayo Clinic: I am four months pregnant and live in an area where there has been a pertussis outbreak. What's the best way to keep my newborn baby safe until he or she can get the vaccine?

Recommended for you

Breastfeeding protects infants from antibiotic-resistant bacteria

October 18, 2018
A recent study completed at the University of Helsinki investigated the amount and quality of antibiotic-resistant bacteria in breast milk and gut of mother-infant pairs. The findings have been published in the journal Nature ...

Inflammation in the womb may explain why some babies are more prone to sepsis after birth

October 9, 2018
Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. A new report in the American Journal ...

Dummies not to blame for common speech disorder in kids

October 9, 2018
New University of Sydney research shows bottles, dummies, and thumb sucking in the early years of life do not cause or worsen phonological impairment, the most common type of speech disorder in children.

'Genes are not destiny' when it comes to weight

October 9, 2018
A healthy home environment could help offset children's genetic susceptibilities to obesity, according to new research led by UCL.

Old drug could have new use helping sick premature babies

October 8, 2018
Researchers from The University of Western Australia, King Edward Memorial Hospital and Curtin University are investigating whether an old drug could be used to help very sick premature babies.

Insufficient sleep associated with risky behavior in teens

October 1, 2018
Adolescents require 8-10 hours of sleep at night for optimal health, according to sleep experts, yet more than 70 percent of high school students get less than that. Previous studies have demonstrated that insufficient sleep ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.