Atrial arrhythmias including atrial fibrillation in congenital heart disease

June 11, 2018, Cardiovascular Innovations and Applications

In the current issue of Cardiovascular Innovations and Applications , Jerold S. Shinbane and Philip M. Chang from the Division of Cardiovascular Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA and the Congenital Heart Center, Departments of Pediatrics and Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USA consider atrial arrhythmias in congenital heart disease.

Atrial arrhythmias, including atrial fibrillation, in the setting of (CHD) are epidemiologically and mechanistically different from those encountered in the general population. These arrhythmias occur at younger ages in patients with CHD, and are frequently degenerative and progressive. The epidemiology, incidence, and prevalence of the spectrum of atrial arrhythmias, including , vary according to the specific CHD type, prior treatment, and residual and ongoing structural and functional sequelae.

The combined impact of incisional scars, abnormal hemodynamics, atrial chamber dilation, and increases in atrial wall thickness and distribution of fibrosis results in a highly dynamic and continuously changing atrial substrate that is highly predisposed to arrhythmias. Given the multiple substrates, individualized therapeutic plans can include pharmacologic therapy, catheter-based ablation, and surgical therapies performed concomitantly with primary surgical intervention for hemodynamically significant sequelae of CHD.

Advanced imaging with CT or MRI can provide valuable information for decision making and procedural planning. Application of novel therapeutic technologies and pharmacologic agents necessitates special considerations when applied to the CHD population and requires greater study in specific subsets of CHD patients.

Explore further: Most common arrhythmia: intra-atrial re-entrant tachycardia

More information: Jerold S. Shinbane et al, Atrial Arrhythmias Including Atrial Fibrillation in Congenital Heart Disease: Mechanisms, Substrate Identification and Interventional Approaches, Cardiovascular Innovations and Applications (2018). DOI: 10.15212/CVIA.2017.0053

Related Stories

Most common arrhythmia: intra-atrial re-entrant tachycardia

August 14, 2017
(HealthDay)—For patients with congenital heart disease and atrial arrhythmias, the most common presenting arrhythmia is intra-atrial re-entrant tachycardia (IART), according to a study published in the Aug. 15 issue of ...

Obesity might raise your risk for A-fib

May 9, 2018
(HealthDay)—Obese people are at increased risk for the heart rhythm disorder atrial fibrillation, which can cause complications such as heart failure and stroke.

Patients who have had an irregular heart beat can't ever be considered 'cured'

May 10, 2018
Patients with an abnormal heart rhythm that can leave them at a higher risk of suffering from stroke still need treatment even after their heart rhythm seems to have returned to normal, say researchers at the University of ...

Greater burden of atrial fibrillation linked to higher stroke risk

May 16, 2018
Among people with intermittently recurring atrial fibrillation who are not taking anti-blood-clotting medications, those whose hearts were in abnormal rhythms longer were three times more likely to have strokes or other types ...

Atrial arrhythmias detected by pacemakers increase risk of stroke

January 11, 2012
An irregular heartbeat that you don't even feel but can be picked up by a pacemaker is associated with a significantly increased risk of stroke, says a new McMaster University study.

Stroke prevention drugs may help reduce dementia risk for atrial fibrillation patients

March 18, 2018
Patients with atrial fibrillation could reduce the risk of dementia by taking stroke prevention medications, according to recommendations published online today in EP Europace, a European Society of Cardiology journal, and ...

Recommended for you

'Smart stent' detects narrowing of arteries

June 19, 2018
For every three individuals who have had a stent implanted to keep clogged arteries open and prevent a heart attack, at least one will experience restenosis—the renewed narrowing of the artery due to plaque buildup or scarring—which ...

Marriage may protect against heart disease / stroke and associated risk of death

June 18, 2018
Marriage may protect against the development of heart disease/stroke as well as influencing who is more likely to die of it, suggests a pooled analysis of the available data, published online in the journal Heart.

Deaths from cardiac arrest are misclassified, overestimated

June 18, 2018
Forty percent of deaths attributed to cardiac arrest are not sudden or unexpected, and nearly half of the remainder are not arrhythmic—the only situation in which CPR and defibrillators are effective—according to an analysis ...

Tick-borne meat sensitivity linked to heart disease

June 15, 2018
University of Virginia School of Medicine researchers have linked sensitivity to an allergen in red meat—a sensitivity spread by tick bites—with a buildup of fatty plaque in the arteries of the heart. This buildup may ...

Tobacco aside, e-cigarette flavorings may harm blood vessels

June 14, 2018
Flavor additives used in electronic cigarettes and related tobacco products could impair blood vessel function and may be an early indicator of heart damage, according to new laboratory research in Arteriosclerosis, Thrombosis ...

The molecules that energize babies' hearts

June 14, 2018
A metabolic process that provides heart muscle with energy fails to mature in newborns with thickened heart walls, according to a Japan–Canada research team.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.