Protein analysis may reveal new cancer treatment targets

cancer
Cancer cell during cell division. Credit: National Institutes of Health

Researchers have used lab technology called mass spectrometry to study the proteins expressed by human cancer cells. The advance, which is described in a new Molecular Oncology article, allows for the quantitation of thousands of tumour proteins over the course of several hours.

The strategy was used to identify several proteins that were over-expressed in a rare form of that did not respond to chemotherapy.

The findings reveal that proteomics—the large scale study of all proteins in a given system—has the potential to quickly provide robust personalised therapeutic options for cancer patients in which standard clinical options have been exhausted.


Explore further

Researchers uncover up to 100 potential drug targets for cancer

More information: Sophia Doll et al. Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient, Molecular Oncology (2018). DOI: 10.1002/1878-0261.12326
Provided by Wiley
Citation: Protein analysis may reveal new cancer treatment targets (2018, June 15) retrieved 16 July 2019 from https://medicalxpress.com/news/2018-06-protein-analysis-reveal-cancer-treatment.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more